甘油三酯脂肪酶异常与子痫前期的相关性
发布时间：2019-08-10 06:47
【摘要】：甘油三酯脂肪酶(ATGL)家族是孕期母体脂质代谢的关键酶,通过水解脂蛋白的甘油三酯和磷脂以释放游离脂肪酸,使母体的脂质转运给胎儿。多项研究表明,子痫前期(PE)孕妇体内多存在脂质代谢紊乱,并与ATGL基因表达异常密切相关。
[Abstract]:Glycerol lipase (ATGL) family is the key enzyme of maternal lipid metabolism during pregnancy. Free fatty acids are released by hydrolyzing lipoprotein glycerides and phospholipids to transport maternal lipids to fetuses. Many studies have shown that most of the pregnant women with preeclampsia (PE) have disorder of lipid metabolism, which is closely related to the abnormal expression of ATGL gene.
【作者单位】： 上海交通大学医学院附属国际和平妇幼保健院;
【基金】：国家自然科学基金
【分类号】：R714.244
，
本文编号：2525037
[Abstract]:Glycerol lipase (ATGL) family is the key enzyme of maternal lipid metabolism during pregnancy. Free fatty acids are released by hydrolyzing lipoprotein glycerides and phospholipids to transport maternal lipids to fetuses. Many studies have shown that most of the pregnant women with preeclampsia (PE) have disorder of lipid metabolism, which is closely related to the abnormal expression of ATGL gene.
【作者单位】： 上海交通大学医学院附属国际和平妇幼保健院;
【基金】：国家自然科学基金
【分类号】：R714.244
，
本文编号：2525037
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