影响原发性阴道癌预后的相关因素分析
发布时间：2019-08-12 11:56
【摘要】：目的:探讨影响原发性阴道癌预后的临床相关因素。方法:回顾性分析2003年1月至2015年1月广西医科大学附属肿瘤医院80例阴道恶性肿瘤患者临床资料。80例患者分为放疗组49例,其中二维放疗(two-dimensional radiotherapy 2DRT)组29例、三维放疗(three-dimensional radiotherapy 3DRT)组20例,比较两组的疗效和并发症;手术组31例,其中腹腔镜手术组16例、开腹手术组15例,评估腹腔镜手术在治疗原发性阴道癌中的可行性。结果:单因素生存分析结果显示FIGO分期、病理类型、肿瘤大小、阴道受侵长度与预后相关(均P0.05),Cox多因素分析显示FIGO分期和病理类型为影响阴道癌预后的独立因素。2DRT组5年生存率20.90%与3DRT组的58.60%进行比较,差异具有统计学意义(P=0.022);2DRT组泌尿系统和消化道并发症的发生率为48.27%(14/29)和51.72%(15/29),分别与3DRT组的15.00%(3/20)和20.00%(4/20)进行比较,差异具有统计学意义(均P0.05)。开腹手术组平均住院(57.00±41.75)天,多于腹腔镜手术组的(29.56±7.3)天,两组比较差异具有统计学意义(P=0.024)。结论:三维放疗及腹腔镜手术的应用,在未降低患者生存率同时可降低并发症,改善患者的生存质量。
[Abstract]:Objective: to investigate the clinical related factors affecting the prognosis of primary vaginal cancer. Methods: the clinical data of 80 patients with vaginal malignant tumor in tumor Hospital affiliated to Guangxi Medical University from January 2003 to January 2015 were analyzed retrospectively. 80 patients were divided into radiotherapy group (n = 49), two-dimensional radiotherapy (two-dimensional radiotherapy 2DRT) group (n = 29) and three-dimensional radiotherapy (three-dimensional radiotherapy 3DRT) group (n = 20). The curative effects and complications of the two groups were compared. 31 cases in the operation group, including 16 cases in the laparoscopic operation group and 15 cases in the open operation group, were used to evaluate the feasibility of laparoscopic surgery in the treatment of primary vaginal cancer. Results: univariate survival analysis showed that FIGO stage, pathological type, tumor size and vaginal invasion length were correlated with prognosis (P < 0.05).), Cox multivariate analysis showed that FIGO stage and pathological type were independent factors affecting the prognosis of vaginal cancer. 2the 5-year survival rate in DRT group was 20.90% compared with 58.60% in 3DRT group, the difference was statistically significant (P 鈮，
本文编号：2525690
[Abstract]:Objective: to investigate the clinical related factors affecting the prognosis of primary vaginal cancer. Methods: the clinical data of 80 patients with vaginal malignant tumor in tumor Hospital affiliated to Guangxi Medical University from January 2003 to January 2015 were analyzed retrospectively. 80 patients were divided into radiotherapy group (n = 49), two-dimensional radiotherapy (two-dimensional radiotherapy 2DRT) group (n = 29) and three-dimensional radiotherapy (three-dimensional radiotherapy 3DRT) group (n = 20). The curative effects and complications of the two groups were compared. 31 cases in the operation group, including 16 cases in the laparoscopic operation group and 15 cases in the open operation group, were used to evaluate the feasibility of laparoscopic surgery in the treatment of primary vaginal cancer. Results: univariate survival analysis showed that FIGO stage, pathological type, tumor size and vaginal invasion length were correlated with prognosis (P < 0.05).), Cox multivariate analysis showed that FIGO stage and pathological type were independent factors affecting the prognosis of vaginal cancer. 2the 5-year survival rate in DRT group was 20.90% compared with 58.60% in 3DRT group, the difference was statistically significant (P 鈮，
本文编号：2525690
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