血清降钙素原对危重患者感染的预测价值

发布时间：2018-10-31 14:29

【摘要】：目的探讨血清降钙素原对危重患者感染的预测价值。方法将50例危重患者作为观察组(根据是否发生感染分为感染组22例,非感染组28例),另选取接受健康体检的50例正常人作为参考组,记录两组患者24 h内血清降钙素原水平及外周血白细胞(WBC)水平,观察危重患者感染发生情况。结果观察组内22例患者出现感染,28例患者无感染,感染发生率为44%。观察组患者内感染组患者血清降钙素原及外周血白细胞水平均明显高于非感染组(P0.05),感染组患者上述指标明显高于参考组(P0.05)。观察组患者中感染组患者治愈成功15例,非感染组患者治愈成功26例,非感染组患者治愈率92.9%明显大于感染组68.2%(P0.05);感染组患者经过积极治疗后,血清降钙素原水平为(0.46±0.17)μg/L,与参考组比较差异无统计学意义(P0.05)。结论通过对血清降钙素原水平进行动态观察能够预测危重患者感染的发生,有助于患者更好的康复。
[Abstract]:Objective to evaluate the predictive value of serum procalcitonin in critically ill patients. Methods 50 critically ill patients were selected as observation group (22 cases were divided into infection group (22 cases) and non-infected group (28 cases) according to whether infection occurred or not, and 50 healthy persons were selected as reference group. The serum procalcitonin level and (WBC) level of peripheral blood leukocytes were recorded in two groups within 24 hours to observe the incidence of infection in critically ill patients. Results in the observation group, there were 22 cases of infection, 28 cases of no infection, the incidence of infection was 44.4%. The levels of serum procalcitonin and peripheral blood leukocytes were significantly higher in the observation group than in the non-infection group (P0.05), and those in the infected group were significantly higher than those in the reference group (P0.05). In the observation group, 15 cases were cured successfully in the infection group and 26 cases in the non-infection group. The cure rate in the non-infection group was 92.9%, which was significantly higher than that in the infection group (68.2%) (P0.05). After active treatment, the serum procalcitonin level was (0.46 卤0.17) 渭 g / L in the infected group, which had no significant difference compared with the reference group (P0.05). Conclusion dynamic observation of serum procalcitonin level can predict the incidence of infection in critically ill patients and be helpful to better rehabilitation.
【作者单位】：河南省济源市人民医院ICU;
【分类号】：R459.7

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