糖尿病及糖调节受损患者口腔念珠菌感染率及阳性率影响因素研究

发布时间：2018-04-03 23:49

本文选题：口腔念珠菌　切入点：感染　出处：《口腔医学研究》2015年06期

【摘要】：目的:研究糖尿病及糖调节受损人群口腔念珠菌感染情况。方法:按照血糖水平将328例血糖异常的患者分为A组(糖尿病组)166例和B组(糖调节受损组)162例。另选择同期在我院门诊体检的血糖正常人群168例为(C组)对照组。统计受检者念珠菌携带、感染、阳性情况,记录受检者空腹血糖、唾液酸碱度、唾液流量,对唾液念珠菌阳性、感染的影响因素行Logistic回归分析。结果:A组口腔念珠菌感染率和阳性率均最高,高于B组和C组(P0.01)。A组、B组唾液酸碱度、唾液流量均低于C组(均P0.01)。A组空腹血糖水平最高,高于B组和C组(P0.01),且B组空腹血糖水平高于C组(P0.01)。结论:年龄、吸烟、配戴义齿和合并系统性疾病等因素与口腔念珠菌检测阳性及感染密切相关,为其主要危险因素。因此,念珠菌感染的高危人群应建立健康的生活习惯、密切监测血糖水平、保持口腔卫生,做好念珠菌感染的防治工作。
[Abstract]:Objective: to study the oral candida infection in patients with diabetes mellitus and impaired glucose regulation.Methods: 328 patients with abnormal blood glucose were divided into two groups: group A (166 cases of diabetes mellitus) and group B (162 cases of impaired glucose regulation group).Another 168 cases of normal blood glucose were selected as control group.The positive rate of Candida spp. The fasting blood glucose, the pH of saliva, the flow of saliva, the positive rate of Candida saliva and the influencing factors of infection were analyzed by Logistic regression analysis.Results the infection rate and positive rate of oral candida were the highest in group 1: 1, higher than those in group B and group C, respectively, and the saliva flow was lower than that in group C (P 0.01), and the fasting blood glucose level in group A was the highest.The fasting blood glucose level in group B was higher than that in group C and group B was higher than that in group C.Conclusion: age, smoking, denture wear and complicated systemic diseases are closely related to the positive detection of oral candida and infection, which are the main risk factors.Therefore, the high risk population of Candida infection should establish healthy living habits, closely monitor blood sugar level, maintain oral hygiene, and do a good job in the prevention and treatment of Candida infection.
【作者单位】：杭州市萧山区第一人民医院口腔科;
【分类号】：R781.5;R587.1

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