渗透树脂和氟化物修复早期龋及抑制再脱矿作用的研究

发布时间：2018-10-25 15:41

【摘要】：目的比较研究渗透树脂和氟化物处理对人磨牙早期龋修复及抑制再脱矿的作用,为临床处理早期龋提供参考依据。方法将人牙样本建立早期龋模型后分成A、B、C、D组,A为空白对照组,不做处理;B为渗透树脂组,渗透树脂处理人工龋;C为渗透树脂+高浓度氟化物组,渗透树脂处理后,每周涂2%氟凝胶;D为渗透树脂+低浓度氟化物组,渗透树脂处理后,每日涂0.05%氟化液。6个月后进行再脱矿处理。显微硬度计测量记录早期龋、3个月、6个月和再脱矿24、72及144 h后的牙釉质表面显微硬度值(vickers hardness number,VHN),同时测定再脱矿24、72及144 h后各标本脱钙液中钙离子浓度值,计算各时间点脱矿液中钙溶出总量。结果在3个月,6个月时,B、C、D组VHN无差别,且均高于A组。再脱矿处理24 h后,C、D组VHN显著高于B组,C、D组间无差异,72,144 h后VHN值D组C组B组。24 h后,D组钙溶出总量显著高于B组,C、D两组间无统计学差异,72,144 h后钙溶出总量D组C组B组。结论渗透树脂和氟化物处理均具有良好的修复早期龋的能力,但单独渗透树脂组在抑制再脱矿方面相对较弱,渗透树脂和低浓度氟化物组在硬度和防止再脱矿方面表现最佳,两者的联合作用无论是在硬度还是再矿化方面效果最佳。
[Abstract]:Objective to compare the effects of osmotic resin and fluoride treatment on the restoration of early caries of human molars and to provide reference for clinical treatment of early caries. Methods Human teeth were divided into two groups: group A as blank control group, group B as osmotic resin to treat artificial caries, group C as high concentration fluoride group treated with osmotic resin, and then treated with osmotic resin. 2% fluoride gel was applied weekly, D was low concentration fluoride group of permeable resin, 0.05% fluoride solution was applied daily after permeating resin treatment, and then demineralized after 6 months. The surface microhardness of enamel was measured by microhardness meter after early caries, 3 months, 6 months and 2472 and 144 hours after demineralization. The calcium ion concentration in the decalcification solution of each sample was also measured after 2472 and 144h of demineralization at the same time. The total amount of calcium in demineralized solution was calculated at each time point. Results at 3 and 6 months, the VHN of group D was higher than that of group A. After 24 hours of demineralization, the VHN of group C was significantly higher than that of group B, but there was no difference between group C and D, and the VHN value of group D was significantly higher than that of group B after 72144 h. After 24 h, the total calcium release of group D was significantly higher than that of group B. there was no statistical difference between group C and D, and the total amount of calcium extracted from group D was significantly higher than group C (group B) 72144 h later. Conclusion the osmotic resin and fluoride treatment have good ability to repair early caries, but the osmotic resin group is relatively weak in inhibiting demineralization, and the osmotic resin and low concentration fluoride group are the best in hardness and preventing demineralization. The combination of the two has the best effect in hardness and mineralization.
【作者单位】：江苏大学附属人民医院口腔科;
【基金】：镇江市科技支撑计划(No:FZ2012043)
【分类号】：R781.1

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