Genius激光与传统手术治疗牙龈增生的术后反应与舒适度临床对比研究

发布时间：2018-11-27 07:46

【摘要】：目的比较Genius激光(水冷型Nd:YAG激光)和手术刀两种方式行牙龈切除术和成形术术后患者的创口愈合情况及舒适度。方法收集牙龈增生患者31例,共计172颗前牙,实验分为激光组和手术刀组,每组各86颗。分别收集术前、术后1周及术后2周的龈沟液(gingival crevicular fluid,GCF),比较GCF量的变化及GCF中转化生长因子-β1(transforming growth factor-β1,TGF-β1)和白细胞介素-1β(interleukin-1β,IL-1β)水平的变化,同时比较患者术前术后牙龈外形色泽、术后1周内的疼痛及出血情况。结果术后1周2组GCF量无明显差异(P=0.091),术后2周GCF量在激光组较手术刀组低,且差异具有统计学意义(P=0.000)。术后1周及术后2周TGF-β1和IL-1β水平在激光组均较手术刀组低,且差异具有统计学意义(P=0.003,P=0.000;P=0.006,P=0.008)。术后第1天和第2天激光组疼痛均较手术刀组低,且差异具有统计学意义(P=0.008,P=0.006),从术后第3天开始2组无统计学差异(P=0.238)。激光组术后均未出血,手术刀组除术后第1天有3例出血外,其余均未出血。术后1周手术刀组牙龈较激光组红肿,术后2周手术刀组有23例患者的牙龈较激光组稍红肿。结论 Genius激光与手术刀比较具有术后创口愈合炎症反应低、创面愈合快和舒适度高的优势,可以作为临床医师行牙周软组织手术的优选方式。
[Abstract]:Objective to compare the wound healing and comfort between Genius laser (water-cooled Nd:YAG laser) and scalpel. Methods Thirty one patients with gingival hyperplasia were divided into laser group (n = 86) and scalpel group (n = 86). Gingival crevicular fluid (gingival crevicular fluid,GCF) was collected before, 1 week and 2 weeks after operation respectively. The changes of GCF, transforming growth factor- 尾 1 (transforming growth factor- 尾 1 TGF- 尾 1 and interleukin-1 尾 (interleukin-1 尾) in GCF were compared. The changes of IL-1 尾, the color and appearance of gingiva before and after operation, the pain and bleeding within 1 week after operation were compared. Results there was no significant difference in the amount of GCF between the two groups at 1 week after operation (P0. 091). The amount of GCF in the laser group was lower than that in the scalpel group 2 weeks after operation, and the difference was statistically significant (P0. 000). The levels of TGF- 尾 1 and IL-1 尾 in the laser group were significantly lower than those in the scalpel group at 1 week and 2 weeks after operation, and the difference was statistically significant (P < 0. 003, P = 0. 000, P = 0. 006, P = 0. 008). The pain in the laser group was significantly lower than that in the scalpel group on the 1st and 2nd day after operation (P0. 008, P0. 006), but there was no statistical difference between the two groups from the 3rd day after operation (P0. 238). No bleeding was found in the laser group, except 3 cases in the scalpel group on the first day after operation. One week after operation, the gingiva in the scalpel group was redder than that in the laser group, and 23 patients in the surgical scalpel group were slightly redder than that in the laser group at 2 weeks after operation. Conclusion compared with scalpel, Genius laser has the advantages of low inflammatory reaction, fast wound healing and high comfort, which can be used as the best choice for clinicians to perform periodontal soft tissue surgery.
【作者单位】：口腔疾病与生物医学重庆市重点实验室;重庆医科大学附属口腔医院牙周科;重庆市高校市级口腔生物医学工程重点实验室;
【基金】：2015重庆市卫生计生委医疗科研项目(2015ZDXM018)~~
【分类号】：R782.1

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