肠易激综合征与精神心理因素的关系

发布时间：2018-06-30 04:39

本文选题：心理因素 + 肠易激综合征　；参考：《新疆医科大学》2010年硕士论文

【摘要】：目的:本研究采用症状自评量表(SCL-90)对肠易激综合征(Irritable bowel syndrome ,IBS)患者及对照组进行评定,进一步探讨IBS发病与精神心理因素之间的关系。方法:应用症状自评量表(SCL-90)对就诊于新疆医科大学第一附属医院消化科并确诊为IBS的30例患者与30例健康对照组进行心理因素评分,IBS患者诊断标准符合罗马III标准,排除吸收不良综合征、血吸虫感染、胃肠道肿瘤、溃疡性结肠炎、Crohn病、肠道菌群失调、肝胆及内分泌疾病、无神经系统及精神疾病史、无药物和酒精滥用。采用SPSS17.0软件进行t检验分析,以P0.05作显著性差异的检验标准。结果:症状自评量表(SCL-90)的结果显示IBS患者躯体化、人际关系、抑郁、焦虑等因子得分均高于对照组,提示IBS患者普遍存在抑郁、焦虑、躯体化、人际关系敏感等异常心理,以焦虑和抑郁更为突出(P0.05)。躯体化、焦虑的因子得分,IBS女性患者高于男性患者,差异有统计学意义(P0.05)。结论:IBS患者普遍存在着不同程度的心理异常,主要表现为抑郁、焦虑、躯体化等症状,IBS女性患者在躯体化及焦虑等因子得分高于男性患者。因此,精神心理因素异常可能在IBS发病机制中起一定的作用。
[Abstract]:Objective: to evaluate the relationship between the pathogenesis of irritable bowel syndrome (IBS) and mental and psychological factors in patients with Irritable bowel syndrome (IBS) by symptom Checklist 90 (SCL-90). Methods: symptom Checklist 90 (SCL-90) was used to evaluate the diagnostic criteria of IBS in 30 patients with IBS and 30 healthy controls in the Department of Digestive Diseases of the first affiliated Hospital of Xinjiang Medical University. Exclusion of malabsorption syndrome, schistosomiasis infection, gastrointestinal neoplasms, ulcerative colitis Crohn's disease, intestinal dysbacteriosis, hepatobiliary and endocrine diseases, no history of nervous system and mental illness, no drug and alcohol abuse. SPSS 17.0 software was used for t test analysis, and P0.05 was used as the test standard of significant difference. Results: the results of symptom Checklist 90 (SCL-90) showed that the scores of somatization, interpersonal relationship, depression and anxiety in IBS patients were higher than those in the control group. Anxiety and depression were more prominent (P0.05). The scores of somatization and anxiety in IBS women were significantly higher than those in men (P0.05). Conclusion the scores of somatization and anxiety in IBS female patients are higher than those in male patients with different degrees of psychological abnormality, and the main symptoms are depression, anxiety, somatization and so on. Therefore, abnormal mental and psychological factors may play a role in the pathogenesis of IBS.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R574;R395

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