经皮穴位电刺激及右美托咪啶镇静镇痛效果的脑电图研究

发布时间：2018-01-29 20:21

本文关键词： 经皮穴位电刺激右美托咪啶定量药物脑电图鼻内滴注　出处：《中华中医药学刊》2016年12期 　论文类型：期刊论文

【摘要】：脑电图自80年代兴起以来,作为一种安全、无创伤的医学检测方法在许多脑神经和组织的疾病如癫痫、脑炎、意识障碍等的诊断中有十分重要的应用价值。近年来,定量药物脑电图利用计算机的强大运算能力和功率谱分析技术,计算药物引起的脑电图相应波段的功率占总功率的百分比的变化,因为脑电变化具有药物剂量相关性,因此可用来指导临床用药。经皮穴位电刺激作为一种无创、安全有效的镇痛方法,具有良好的临床前景。右美托咪啶作为一种α肾上腺素能受体激动剂,具有镇静、镇痛、抗焦虑等作用,由于其本身呼吸抑制少,可产生近似自然状态的睡眠并保留唤醒功能等优点而广泛应用于术中镇静镇痛及ICU镇静等,特别是经鼻给药方法,由于其方便性、无创性、患者舒适度高等优点而在临床工作中正逐步推广开来。对于右美托咪啶临床应用的各方面,临床工作者一直没有停下研究的脚步。就右美托咪啶的药理作用、局麻手术中的应用现状、经皮穴位电刺激对脑电图的影响及脑电图用于药物麻醉深度监测研究的现状进行综述。
[Abstract]:Since its rise in 80s, EEG has been used as a safe, non-invasive medical method for the detection of many neurological and tissue diseases such as epilepsy and encephalitis. In recent years, quantitative drug electroencephalogram (QDEEG) has made use of the powerful computing power of computer and power spectrum analysis technology. Calculate changes in the percentage of power in the corresponding band of electroencephalogram (EEG) caused by drugs as a percentage of total power, as EEG changes are dose-dependent. As a non-invasive, safe and effective analgesic method, it has a good clinical prospect. Dexmetidine as a 伪 -adrenergic receptor agonist. It has many advantages, such as sedation, analgesia, anti-anxiety and so on. It is widely used in intraoperative sedation, analgesia, ICU sedation and so on, because of its low respiratory inhibition, similar to the natural state of sleep and retain the function of arousal. In particular, the transnasal drug delivery method, due to its convenience, non-invasive, high comfort of patients and so on, is gradually popularized in clinical work. For all aspects of clinical application of dexmetidine. The clinical workers have not stopped to study the pharmacological effect of dexmetidine on the current application of local anesthesia surgery. The effect of transcutaneous acupoint electrical stimulation on EEG and the current situation of EEG used in monitoring the depth of drug anesthesia were reviewed.
【作者单位】：沈阳市沈河区中医院;中国医科大学附属盛京医院麻醉科;
【基金】：辽宁省自然科学基金项目(20102212) 中国医科大学盛京医院三新项目(2015PS57J)
【分类号】：R614
【正文快照】： 笔者就右美托咪啶的药理作用、局麻手术中的应用现状、经皮穴位电刺激对脑电图的影响及脑电图用于药物麻醉深度监测研究的现状进行综述。1脑电图用于临床麻醉监测1.1脑电图用于麻醉深度监测麻醉是为了使患者在手术过程中对伤害性刺激无反应、无回忆,确保手术安全、顺利进行的

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