绝经后不同骨关节退行性疾病与骨质疏松程度的相关性研究

发布时间：2018-01-31 21:29

  本文关键词： 骨质疏松 骨密度 骨关节退行性疾病　出处：《中国骨质疏松杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的探讨绝经后女性不同骨关节退行性疾病的临床特点及与骨密度的关系,为防治绝经后骨关节退行性疾病提供依据。方法选取2013年9月至2016年3月在我院收治的959例绝经后女性患者,取腰椎和股骨颈处的最大的骨密度值及T值作为研究对象,按不同骨关节退行性疾病分为脆性骨折组、腰椎退行性病变组、膝骨关节炎组及无明显骨关节疾病对照组。采用SPSS 19.0软件进行统计学分析。结果 (1)各组间腰椎BMD值及T值的差异具有统计学意义(P0.05),其中腰椎退行性病变组患者的腰椎骨密度值和T值均比其他3组明显减低(P0.05),膝骨关节炎组骨密度值和T值均高于其他3组(P0.05);(2)各组间股骨颈BMD值及T值的差异具有统计学意义(P0.05),其中脆性骨折组患者的股骨颈骨密度值和T值均比其他3组明显减低(P0.05),膝骨关节炎组骨密度值和T值均高于其他3组(P0.05)。结论在绝经后女性患者中,脆性骨折与骨质疏松的关系最为密切,而其他骨关节疾病也在不同程度上与骨质疏松程度存在显著相关性,在治疗骨关节疾病的同时也要重视骨质疏松症的防治。
[Abstract]:Objective to investigate the clinical characteristics of different osteoarticular degenerative diseases in postmenopausal women and their relationship with bone mineral density (BMD). Methods 959 postmenopausal women who were admitted to our hospital from September 2013 to March 2016 were selected to provide evidence for the prevention and treatment of postmenopausal osteoarthritis. The maximum bone mineral density (BMD) and T value of lumbar spine and femoral neck were taken as the research objects. According to different osteoarticular degenerative diseases, they were divided into brittle fracture group and lumbar degenerative disease group. SPSS 19.0 software was used for statistical analysis. Results the BMD and T values of lumbar vertebrae in each group were significantly different (P < 0.05). P0.05). The bone mineral density and T value of lumbar vertebrae in the group of lumbar degenerative diseases were significantly lower than those in the other three groups, and the bone mineral density and T value in the group of knee osteoarthritis were higher than those in the other three groups. (2) the difference of BMD value and T value of femoral neck was statistically significant (P 0.05). The bone mineral density and T value of femoral neck in fragile fracture group were significantly lower than those in other three groups (P 0.05). Bone mineral density (BMD) and T value in knee osteoarthritis group were higher than those in the other three groups (P 0.05). Conclusion in postmenopausal women, brittle fracture is most closely related to osteoporosis. Other bone and joint diseases also have a significant correlation with the degree of osteoporosis in varying degrees. We should pay attention to the prevention and treatment of osteoporosis as well as the treatment of osteoarthrosis.
【作者单位】： 广州医科大学附属第二医院;
【基金】：国家自然科学基金资助(81574002)
【分类号】：R580;R684
【正文快照】： 随着社会人口老龄化,近年来骨与关节的退行性疾病的发病率越来越高,严重影响了人们的生活质量,给患者的家庭和整个社会带来了重大的负担;而这些骨关节疾病常常合并骨质疏松症(osteoporosis,OP),尤其在绝经后女性中更为常见。骨密度(bone mineral density,BMD)是诊断骨质疏松症，

本文编号：1480045