血清生物学指标在脊柱内固定融合术后感染患者中的诊断价值

发布时间：2018-02-06 02:28

本文关键词： 血清生物学脊柱内固定融合术感染诊断价值　出处：《中华医院感染学杂志》2017年15期 　论文类型：期刊论文

【摘要】：目的探讨血清生物学指标在脊柱内固定融合术后感染患者中的诊断价值,旨在为临床诊断和治疗提供一定参考意义。方法选择2014年6月-2016年6月期间于医院收治的因胸腰椎骨折、腰椎滑脱症、腰椎间盘突出症等行脊柱内固定融合术术后感染患者78例为观察组,选自同期收治的未感染患者100例为对照组;分析术后感染患者病原菌分布、耐药性及两组患者临床指标。结果术后感染78例共培养病原菌69株,以革兰阴性菌为主,共49株占71.01%;铜绿假单胞菌、肺炎克雷伯菌对庆大霉素和环丙沙星耐药率较高,均80.00%;观察组血清C-反应蛋白(CRP)、碱性磷酸酶(ALP)、肌酸激酶(CK)均显著高于对照组,差异有统计学意义(P0.05)。结论血清生物学指标CRP、ALP、CK对脊柱内固定融合术后感染患者具有重要诊断价值,且术后感染以革兰阴性菌为主。
[Abstract]:Objective to evaluate the diagnostic value of serum biological markers in patients with infection after spinal fusion. Methods from June 2014 to June 2016, patients with thoracolumbar fractures and spondylolisthesis were selected. 78 cases of infection after spinal internal fixation fusion were selected as observation group and 100 cases as control group. Results 69 strains of pathogens were cultured in 78 cases of postoperative infection, 49 strains were Gram-negative bacteria, and 49 strains accounted for 71.01%. Pseudomonas aeruginosa and Klebsiella pneumoniae had higher resistance to gentamicin and ciprofloxacin, both 80.00. The levels of serum C-reactive protein (CRP), alkaline phosphatase (ALP), creatine kinase (CK) in the observation group were significantly higher than those in the control group. The difference was statistically significant (P 0.05). Conclusion the serum biological index CRP- ALPCK has important diagnostic value in patients with infection after spinal internal fixation fusion. Gram-negative bacteria were the main infection after operation.
【作者单位】：瑞安市人民医院脊柱外科;
【基金】：浙江省医药卫生基金资助项目(2014KYB315)
【分类号】：R687.3

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