Zero-P颈椎前路内固定系统修复多节段脊髓型颈椎病

发布时间：2018-02-28 20:49

本文关键词： 脊柱融合术内固定器随访研究组织工程骨科植入物脊柱植入物颈椎病融合固定内固定前路 Zero-P 脊髓病变开放手术生物相容性　出处：《中国组织工程研究》2017年11期 　论文类型：期刊论文

【摘要】：背景:Zero-P零切迹颈椎前路内固定系统是近年来治疗脊髓型颈椎病的重要手段,通过Zero-P内固定可实现对脊髓及神经的有效减压,恢复颈椎生理曲度,稳定性良好。目的:探讨采用Zero-P颈椎前路内固定系统治疗多节段脊髓型颈椎病的生物相容性。方法:纳入62例采用Zero-P颈椎前路内固定系统治疗的多节段脊髓型颈椎病患者,其中合并2个颈椎节段病变患者47例,3个节段13例,4个节段2例。观察术后1,6,12,24个月颈椎目测类比评分、日本骨科学会(JOA)评分及颈椎功能障碍指数,评价临床疗效;同时观察术后并发症发生率、椎间隙高度及颈椎Cobb角变化。结果与结论:(1)54例患者在治疗后2年内通过门诊或电话联系获得随访,平均手术时间(102.00±32.41)min,平均术中出血量(62.45±18.36)m L;(2)2例患者术后1 d出现咽喉轻度不适感,6 d后症状自行解除,其余患者术后各时间点均未出现其他并发症;(3)术后1,6,12,24个月,患者目测类比评分及颈椎功能障碍指数低于术前(P0.05),颈椎JOA评分高于术前(P0.05),颈椎Cobb角大于术前(P0.05),均较术前明显改善(P0.05),术后各时间点病变节段椎间隙高度明显高于术前(P0.05);依据JOA评分结果,54例患者中优34例,良14例,可6例,差0例,优良率为89%;(4)结果表明,Zero-P颈椎前路融合内固定系统治疗多节段颈椎病具有良好效果,可有效缓解患者症状,恢复颈椎生理曲度及高度,具有良好的生物相容性。
[Abstract]:Background: Zero-P zero notch anterior cervical fixation system is an important method for the treatment of cervical Spondylotic myelopathy in recent years. Zero-P internal fixation can effectively decompress the spinal cord and nerves and restore the physiological curvature of the cervical spine. Objective: to investigate the biocompatibility of Zero-P anterior cervical fixation system in the treatment of multilevel cervical Spondylotic myelopathy. Methods: 62 patients with multilevel cervical Spondylotic myelopathy treated with Zero-P anterior internal fixation system were included. Among them, 47 cases were complicated with 2 cervical segment lesions, 13 cases with 3 segments and 2 cases with 4 segments. The cervical visual analogue score, JOAA score and cervical spine dysfunction index were observed in 1 month, 12 cases, 24 months after operation, and the clinical efficacy was evaluated. At the same time, the incidence of postoperative complications, the height of intervertebral space and the changes of cervical Cobb angle were observed. The mean operative time was 102.00 卤32.41 min, the average intraoperative bleeding volume was 62.45 卤18.36 min / L and the symptoms of 2 cases with mild pharynx and larynx discomfort were relieved 1 day after operation. No other complications were found in other patients at each time point after operation. The visual analogue score and cervical spine dysfunction index were lower than those before operation (P 0.05), the cervical JOA score was higher than that of preoperative P 0.05 and the cervical Cobb angle was higher than that of preoperation (P 0.05), which was significantly improved than that of preoperation. The height of intervertebral space at different time points after operation was significantly higher than that of surgery. According to the results of JOA score, 34 cases were excellent in 54 cases. The results showed that Zero-P anterior cervical fusion and internal fixation system had a good effect in the treatment of multilevel cervical spondylosis, and could effectively relieve the symptoms of the patients and restore the physiological curvature and height of the cervical spine. It has good biocompatibility.
【作者单位】：深圳市中医院;广州中医药大学第四临床医学院;
【分类号】：R687.3

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