重型颅脑损伤致严重凝血功能异常患者的危险因素分析

发布时间：2018-03-02 14:34

本文选题：重型颅脑损伤　切入点：凝血功能异常　出处：《广东医学》2017年S2期 　论文类型：期刊论文

【摘要】：目的探讨重型颅脑损伤患者出现严重凝血功能异常的危险因素。方法将96例重型颅脑损伤患者的性别、年龄、受伤至入院时间、入院时格拉斯哥昏迷评分、是否多器官损伤、是否低血压、是否低血氧、是否手术治疗及CT复查是否出现颅内血肿增大进行记录。同时对入院时凝血酶原时间、活化部分凝血活酶时间、纤维蛋白原及血小板情况进行记录,在住院过程中对患者的凝血功能情况进行追踪。如患者出现严重凝血功能异常视为阳性事件。采用二分类逐步logistic回归分析数据。结果患者的年龄、格拉斯哥昏迷评分及多器官损伤是患者发生凝血功能严重异常的独立影响因素。结论重型颅脑损伤患者如果存在高龄、格拉斯哥昏迷评分低及多器官损伤,严重凝血功能异常的发生率较高。
[Abstract]:Objective to investigate the risk factors of severe coagulation dysfunction in patients with severe craniocerebral injury. Methods 96 patients with severe craniocerebral injury were divided into three groups: sex, age, time from injury to admission, Glasgow coma score on admission, and multiple organ injury. At the same time, the time of prothrombin, activated partial thromboplastin, fibrinogen and platelet were recorded. In the course of hospitalization, the coagulation function of the patients was tracked. If the patients with severe abnormal coagulation function were regarded as positive events, the data of stepwise logistic regression analysis were used to analyze the age of the patients. Glasgow coma score and multiple organ injury were independent influencing factors of severe abnormal coagulation function in patients with severe craniocerebral injury. Conclusion if the patients with severe craniocerebral injury have old age, Glasgow coma score is low and multiple organ injury. The incidence of severe coagulation dysfunction was higher.
【作者单位】：深圳市罗湖区人民医院神经外科;
【基金】：深圳市罗湖区软科学研究计划项目(编号:罗科[2014]24号-32)
【分类号】：R651.15

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