精准医学在结直肠外科中的内涵与临床实践

发布时间：2018-03-14 02:35

本文选题：结直肠肿瘤　切入点：结直肠外科手术　出处：《中华普外科手术学杂志(电子版)》2016年03期 　论文类型：期刊论文

【摘要】：2015年,美国医生Francis S.Collins在著名的新英格兰医学杂志上撰文介绍了精准医学的概念。精准医学是近年来出现的新的医学概念。它是以分子基因为基础实现对疾病的诊断和治疗。我们已经进入了一个精准医学的时代。我们也经历了经验医学,循证医学,现在又进入了精准医学的时代。今天,在结直肠癌领域,我们已经看到:精准医学已经在结直肠癌的姑息治疗中发挥着重要作用,如:常用的爱必妥,安维汀和帕尼单抗等。因此,结直肠外科医生应该认真地学习精准医学的概念,了解精准医学在结直肠领域的独特作用。同时,我们也要应用精准医学的概念去认识和解决结直肠癌领域亟待解决的科学问题。而且,我们也要看到精准医学的局限性,客观公正地评价精准医学。
[Abstract]:2015, Francis S. Collins, an American doctor, wrote about the concept of precision medicine in the famous New England Journal of Medicine. Precision medicine is a new medical concept that has emerged in recent years. It is based on molecular genes for the diagnosis and treatment of diseases. Therapy. We have entered an era of precision medicine. We have also experienced empirical medicine, Evidence-based medicine has now entered the era of precision medicine. Today, in the field of colorectal cancer, we have seen that precision medicine has played an important role in palliative treatment of colorectal cancer, such as: commonly used love. Therefore, colorectal surgeons should seriously learn the concept of precision medicine and understand the unique role of precision medicine in the field of colorectal cancer. We should also apply the concept of precision medicine to understand and solve the urgent scientific problems in the field of colorectal cancer, and we should also see the limitations of precision medicine and evaluate it objectively and fairly.
【作者单位】：北京大学临床肿瘤医院;
【基金】：国家自然科学基金(81030040,30872467) 科技部十一五支撑课题(2008BA152B03) 国家863(2012AA02A506) 北京自然科学基金(7132052)~~
【分类号】：R656

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