右美托咪定预防经皮肾镜碎石取石术患者全身麻醉拔管期躁动的临床观察

发布时间：2018-03-15 03:36

本文选题：右美托咪定　切入点：经皮肾镜碎石术　出处：《重庆医学》2017年28期 　论文类型：期刊论文

【摘要】：目的观察右美托咪定预防经皮肾镜碎石取石术患者全身麻醉拔管期躁动的临床效果。方法选择美国麻醉医师协会(ASA)Ⅰ~Ⅱ级择期行经皮肾镜碎石取石术的患者60例,分为右美托咪定组(DEM组)和生理盐水组(NS组),每组30例。于手术结束前30min,DEM组静脉泵注右美托咪定0.5μg/kg,NS组泵注等剂量的生理盐水,10min泵完。记录两组患者在麻醉诱导前(T_0)、缝皮结束时(T_1)、拔管即刻(T_2)、拔管后5min(T_3)、拔管后10min(T_4)时的心率(HR)、平均动脉压(MAP),观察两组睁眼时间、拔管时间及拔管期躁动发生率。结果 DEM组患者在T_2、T_3、T_4时点的MAP、HR低于NS组(P0.05),NS组在T_2、T_3、T_4时点的MAP、HR较T_0高(P0.05);DEM组患者全身麻醉拔管期躁动总发生率明显低于NS组,差异有统计学意义(P0.01);两组患者睁眼时间、拔管时间差异无统计学意义(P0.05)。结论在全身麻醉下经皮肾镜碎石取石手术结束前30min泵注右美托咪定0.5μg/kg可有效减少拔管期躁动的发生。
[Abstract]:Objective to observe the clinical effect of dexmetomidine in preventing restlessness during extubation of general anesthesia in patients undergoing percutaneous nephrolithotomy. 30 cases in each group were injected with dexmetomidine 0.5 渭 g 路kg ~ (-1) NS for 10 minutes before the end of operation. Before anesthesia induction, the patients in both groups were recorded before anesthesia induction. The patients in the control group were treated with dexmetomidine 0.5 渭 g 路kg ~ (-1) 路kg ~ (-1) 路kg ~ (-1) 路L ~ (-1) ~ (-1) 路L ~ (-1) ~ (-1). At the end of skin suture, T _ 1T _ 1, T _ 2T _ 2 immediately after extubation, 5 min after extubation and T _ 3 at 10 min after extubation and 10 min after extubation, the heart rate and mean arterial pressure were observed to observe the time of eye opening in the two groups. Results the total incidence of restlessness in the DEM group was significantly lower than that in the NS group in the general anesthesia extubation stage in the DEM group compared with that in the NS group at the time point of T20 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0 / T0. Results the total incidence of restlessness in the DEM group was significantly lower than that in the NS group at the time of T20 / T0 / T0 / T0 / T0 / T0.05Dem. There was no significant difference in the time of eye opening and extubation between the two groups. Conclusion the restlessness during extubation can be effectively reduced 30 minutes before the end of percutaneous nephrolithotomy under general anesthesia by intravenous injection of dexmetomidine 0.5 渭 g / kg.
【作者单位】：昆明医科大学第二附属医院麻醉科;
【分类号】：R614

【相似文献】