舒芬太尼联合伤口持续输注罗哌卡因用于心脏手术后的镇痛效果分析

发布时间：2018-03-17 16:35

本文选题：持续伤口输注　切入点：镇痛　出处：《重庆医学》2017年08期 　论文类型：期刊论文

【摘要】：目的评价舒芬太尼静脉自控镇痛联合伤口持续输注罗哌卡因用于心脏手术后的镇痛效果。方法选择体外循环下开胸心脏手术患者100例,按照数字随机法分为舒芬太尼组(S组)和舒芬太尼联合伤口持续输注罗哌卡因组(L组)。S组单用舒芬太尼静脉自控镇痛,L组在S组基础上联合伤口持续输注0.36%罗哌卡因镇痛,均在术毕开始泵注至术后48h。分别记录术后24、48h患者静态及动态疼痛视觉模拟评分、Ramsay镇静评分、按压镇痛泵总次数及剂量、不良反应发生率、辅助镇痛药使用率。评价术后48h患者整体镇痛满意度及伤口感染率。结果两组各时点静态、动态疼痛视觉模拟评分、Ramsay镇静评分、按压镇痛泵总次数及剂量、不良反应发生率及辅助镇痛药使用率组间比较,差异均无统计学意义(P0.05);两组患者术后48h整体镇痛满意度及伤口感染率比较,差异无统计学意义(P0.05)。结论伤口持续输注罗哌卡因不能改善心脏手术后舒芬太尼自控静脉镇痛效果、减少舒芬太尼使用剂量和不良反应发生率。
[Abstract]:Objective to evaluate the analgesic effect of sufentanil patient-controlled analgesia combined with continuous infusion of ropivacaine after cardiac surgery. Methods 100 patients undergoing open heart surgery under cardiopulmonary bypass were selected. The patients were randomly divided into sufentanil group (S group) and sufentanil combined with ropivacaine group (group L). Group S was treated with sufentanil for patient-controlled intravenous analgesia alone and group L combined with continuous wound infusion of 0.36% ropivacaine on the basis of group S. The visual analogue score of static and dynamic pain and Ramsay sedative score, the total number and dosage of the pump, and the incidence of adverse reactions were recorded. The total analgesic satisfaction and wound infection rate were evaluated at 48 hours after operation. Results the static and dynamic visual analogue score of pain and Ramsay sedative score, the total number and dosage of the analgesic pump were evaluated in the two groups at each time point. There was no significant difference in the incidence of adverse reactions and the rate of use of auxiliary analgesics between the two groups, and the overall analgesic satisfaction and wound infection rate were compared between the two groups at 48 hours after operation. Conclusion continuous infusion of ropivacaine can not improve the analgesic effect of sufentanil after cardiac surgery and reduce the dosage and adverse reaction of sufentanil.
【作者单位】：三峡大学人民医院麻醉科;三峡大学人民医院药学部;
【分类号】：R614

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