自体颅骨修补术后并发症及其相关危险因素的分析

发布时间：2018-03-19 02:03

本文选题：重型颅脑损伤　切入点：去骨板减压　出处：《宁夏医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的探究自体颅骨修补术后并发症及其相关危险因素的分析。资料与方法回顾性分析2011年1月至2014年11月按相关标准纳入132例宁夏医科大学总医院神经外科的需行自体颅骨修补的患者,分析患者性别、年龄、手术时间、颅骨缺损面积、手术间隔时间与术后并发症的关系,先进行单因素统计分析,将差异有统计学意义的因素再进行Logistic多因素回归分析,筛选出术后并发症的独立危险因素。结果1、自体颅骨修补术后并发症发生率为14.39%(19/132),其中术后出现头皮下积液3例,切口感染3例,骨质吸收发生1例,硬膜外积液发生2例,硬膜下积液发生4例,术后继发性癫痫发生最多为6例,发生率为4.55%(6/132)。2、经单因素分析发现术后并发症的危险因素为:年龄(P=0.002)、颅骨缺损面积(P=0.001)。经Logistic多因素回归分析显示,年龄(P=0.031)、颅骨缺损面积(P=0.001)是影响术后并发症发生的独立危险因素。3、性别对术后并发症的发生差异无统计学意义(P=0.152),手术时间对术后并发症的发生差异无统计学意义(P=0.332),手术间隔时间对术后并发症的发生差异无统计学意义(P=0.384)。结论本研究中,颅骨修补术后并发症发生率较高,达到14.4%(19/132),包括继发性癫痫,硬膜下积液,切口感染,头皮下积液,硬膜外积液,骨质吸收等。其中术后继发性癫痫发生率最高,达到4.5%。患者的年龄和颅骨缺损面积是影响自体颅骨修补术后并发症发生的独立危险因素。
[Abstract]:Objective to investigate the complications and related risk factors after autogenous cranioplasty. Data and methods retrospective analysis of 132 cases of neurosurgery in Ningxia Medical University General Hospital from January 2011 to November 2014. Patients undergoing autogenous skull repair, Sex, age, operative time, area of skull defect, operative interval and postoperative complications were analyzed. Univariate statistical analysis was performed, and then Logistic multivariate regression analysis was carried out. Results 1 the incidence of complications after autologous cranioplasty was 14.39 / 132%, including 3 cases of subscalp effusion, 3 cases of incision infection, 1 case of bone resorption, 2 cases of epidural effusion, 1 case of postoperative complications, 1 case of bone resorption, 2 cases of epidural effusion, 1 case of incision infection, 1 case of bone resorption and 2 cases of epidural effusion. There were 4 cases of subdural effusion and 6 cases of secondary epilepsy after operation. The incidence rate was 4.55 / 13 / 2. By univariate analysis, the risk factors of postoperative complications were as follows: age (P < 0.002), cranial defect area (P < 0.001), and Logistic multivariate regression analysis. Age and skull defect area were independent risk factors for postoperative complications. There was no significant difference between sex and postoperative complications (P = 0.152), but there was no significant difference in operative time and postoperative complications (P = 0.332P = 0.332P = 0.332P = 0.332P = 0.332P = 0.332P = 0.332P < 0.01). There was no significant difference between the interval time and postoperative complications. Conclusion in this study, there is no significant difference in the incidence of postoperative complications. The incidence of complications after cranioplasty was relatively high, reaching 14.4% of 132um, including secondary epilepsy, subdural effusion, incisional infection, subscalp effusion, epidural effusion, bone resorption and so on. The incidence of post-operative secondary epilepsy was the highest. The age of the patient and the area of skull defect were independent risk factors for complications after autogenous cranioplasty.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R651.1

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