微等离子束治疗增生性瘢痕的临床研究

发布时间：2018-03-23 23:09

本文选题：微等离子束　切入点：增生性瘢痕　出处：《上海交通大学》2015年硕士论文

【摘要】：目的:微等离子束是一种独特的通过微剥脱射频技术传递射频能量的微小等离子体集束,可以剥脱和穿透皮肤组织,在治疗区域内造成可控深度的少量热损伤及在皮肤上形成聚焦的微创通道,而周围的正常组织不受影响。临床上常用于改善凹陷性瘢痕,痤疮瘢痕,妊娠纹等,但其应用于增生性瘢痕的治疗尚处于起步阶段。本研究旨在探讨应用微等离子束治疗增生性瘢痕的临床疗效和安全性。方法:本研究选取17例增生性瘢痕的患者,其中11例女性和6例男性;年龄16岁到47岁,平均年龄29.3岁;面部10例,颈部3例,上肢3例,胸部1例。治疗前温哥华瘢痕评定量表(VSS)评分为4分到9分。应用闪耀离子束瘢痕治疗仪(以色列飞顿公司)对疤痕进行2-4次治疗,每次间隔8周。通过治疗前后的VSS评分来评价疗效,并随访患者满意度和可能发生的副作用。结果:末次治疗后随访2-4月,所有病例的瘢痕均有改善,治疗后VSS评分均显著降低,平均值从6.4降至4.4,具有统计学差异(P0.05)。所有患者均认为治疗有效,局部症状明显改善。副作用主要为皮肤一过性红肿和类似日晒后状态,未观察到色素沉着等不良反应,患者外出或工作等日常活动未受影响。结论:微等离子束进行增生性瘢痕的治疗,是一种有效、安全的方法,但尚需随访其远期疗效和不良反应。
[Abstract]:Objective: micro iso-ion beam is a unique micro plasma cluster which can transfer radio frequency energy through microstrip radiofrequency, which can strip and penetrate the skin tissue. In the treatment area, a small amount of heat damage is caused by controlled depth and a focused minimally invasive channel is formed on the skin, while the surrounding normal tissue is not affected. Clinically, it is often used to improve sunken scar, acne scar, pregnancy stria, etc. But the treatment of hypertrophic scar is still in its infancy. The purpose of this study was to investigate the clinical efficacy and safety of microplasma beam in treating hypertrophic scar. Methods: 17 patients with hypertrophic scar were selected in this study. There were 11 women and 6 men, aged 16 to 47, with an average age of 29.3 years, 10 faces, 3 neck, 3 upper limbs, One case of chest. Before treatment, the VSS score of Vancouver scar rating scale was 4 to 9. The scar was treated 2-4 times with blazed ion beam scar therapy instrument (Fiden Company of Israel). The efficacy was evaluated by VSS score before and after treatment, and the patients' satisfaction and possible side effects were followed up. Results: after 2 to 4 months of follow-up, all patients' scars were improved. After treatment, the VSS score decreased significantly, the average value decreased from 6.4 to 4.4, with statistical difference (P 0.05). All the patients considered the treatment effective and the local symptoms were significantly improved. The side effects were mainly transient redness of skin and similar sunburn state. No adverse reactions such as pigmentation were observed, and the patients' daily activities, such as going out or working, were not affected. Conclusion: it is an effective and safe method to treat hypertrophic scar with micro-ion beam. But it is necessary to follow up its long-term effects and adverse reactions.
【学位授予单位】：上海交通大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R62

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