神经外科患者术后颅内感染危险因素分析

发布时间：2018-03-31 19:40

本文选题：神经外科　切入点：颅内感染　出处：《中华医院感染学杂志》2016年08期

【摘要】：目的探讨神经外科患者术后颅内感染危险因素,为临床提供依据,尽量减少和避免颅内感染的风险。方法以2011年3月-2015年7月神经外科收治的344例开颅术患者为研究对象,根据术后感染状况的结果,用logistic回归分析颅内感染的独立危险因素,数据采用SPSS 19.0软件进行统计分析。结果共调查344例患者,感染32例,感染率为9.30%;脑室管引流、ASA评分、脑脊液漏、手术时间为发生感染的相关危险因素(P0.05);多因素非条件logistic回归分析结果显示,脑室外引流、ASA评分、脑脊液漏和手术时间是神经外科开颅手术患者在术后发生颅内感染的独立危险因素(P0.05)。结论导致神经外科术后并发颅内感染的因素是多方面的,特别要注意室外引流、ASA评分、脑脊液漏和手术时间等危险因素,以改善患者预后,及时制定针对性地预防措施,提高治疗效果,降低术后感染率。
[Abstract]:Objective to explore the risk factors of intracranial infection in neurosurgical patients after operation, to provide evidence for clinical practice and to minimize and avoid the risk of intracranial infection. Methods 344 patients with craniotomy admitted in neurosurgery from March 2011 to July 2015 were studied. According to the results of postoperative infection, the independent risk factors of intracranial infection were analyzed by logistic regression analysis. The data were statistically analyzed by SPSS 19.0 software. Results A total of 344 patients were investigated, 32 cases were infected, the infection rate was 9.30%, and the ventricular tube drainage score was 9.30%. Cerebrospinal fluid leakage (CSF) and operative time were the risk factors associated with infection (P 0.05). Multivariate logistic regression analysis showed that ventricular drainage was assessed by ASA score. Cerebrospinal fluid leakage and operative time are independent risk factors for intracranial infection in patients undergoing neurosurgery craniotomy. Conclusion there are many factors leading to intracranial infection after neurosurgery, especially outdoor drainage and ASA score. The risk factors such as cerebrospinal fluid leakage and operative time were used to improve the prognosis of the patients, to formulate timely preventive measures, to improve the therapeutic effect and to reduce the postoperative infection rate.
【作者单位】：襄阳市中心医院湖北文理学院附属医院神经外科;
【基金】：湖北省科技厅自然科学基金资助项目(2102FFC05901)
【分类号】：R651.11

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