沿不同缝合方向皮肤应力的有限元分析

发布时间：2018-04-01 21:33

本文选题：瘢痕　切入点：瘢痕疙瘩　出处：《中国组织工程研究》2017年04期

【摘要】：背景:力学因素在皮肤伤口愈合和瘢痕形成的过程中有重要作用。目前利用有限元方法模拟、分析及优化各种缝合方式并精确指导外科手术,成为一个重要课题。目的:通过建立皮肤有限元模型,分析单纯间断缝合不同缝合方向的皮肤伤口应力分布,为研究瘢痕的形成提供基础数据。方法:通过猪背皮肤单轴拉伸试验,为人体皮肤力学性能提供参考;利用ABAQUS建立正交各向异性的皮肤伤口模型,并计算沿不同缝合方向皮肤伤口的应力分布。结果与结论:(1)皮肤的各向异性对皮肤伤口缝合应力影响明显,沿朗格氏线(Langer's lines)方向的弹性模量大于其垂直方向的弹性模量;(2)伤口缝合应力按照朗格氏线方向伤口、朗格氏线方向偏转30°伤口、朗格氏线方向偏转45°伤口、垂直朗格氏线方向伤口的顺序依次增大;(3)结果提示,临床手术切口宜沿着朗格氏线方向,除此之外,切口偏转朗格氏线一定的角度也可以减小缝合应力。
[Abstract]:Background: mechanical factors play an important role in skin wound healing and scar formation. Simulated by finite element method at present, analysis and optimization of various methods and accurate guidance of surgical suture, has become an important issue. Objective: to establish the finite element analysis model of the skin, simple interrupted suture of different suture wound stress direction the distribution, provide the basic data for the research on the formation of scar. Methods: the pig skin uniaxial tensile tests, to provide reference for the mechanical properties of human skin; skin wound model using ABAQUS to establish orthogonal anisotropy, and calculate the stress distribution along the different direction of skin wound suture. Results and conclusion: (1) anisotropy skin to skin wound closure stress significantly, along the line of kerckring (Langer's lines) and elastic modulus is greater than the vertical direction; (2) wound closure stress According to the wound kerckring line direction, the direction of 30 DEG kerckring wire wound, kerckring line direction deflection 45 degrees vertical line direction of the wound, wound kerckring order increases; (3) the results suggest that clinical surgical incision should be kerckring along the line direction, in addition, deflexio kerckring line incision angle can reduce suture should force.

【作者单位】：太原理工大学应用力学与生物医学工程研究所;太钢总医院山西省烧伤救治中心;
【基金】：国家自然科学基金(11372208) 山西省自然科学基金(2013011002-4)~~
【分类号】：R641;R318.01

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