封堵术改善房间隔缺损患者的远期疗效

发布时间：2018-04-05 10:28

  本文选题：超声心动图　切入点：房间隔缺损　出处：《实用医学杂志》2017年05期

【摘要】：目的:运用超声心动图评价房间隔缺损(ASD)成功施行封堵术后远期临床疗效。方法:采用前瞻性队列研究方法,共纳入符合标准患者70例。治疗组48例,采用封堵术治疗+常规治疗;对照组22例,常规治疗。采用经胸超声心动图(TTE)技术评价患者术前、术后1年内各时间点右房、右室结构及功能的变化。结果:结构方面,治疗组与对照组比较,RAEDd、RAEDdd、IVC、RVEDd、RVEDdz、RVEDdc、PASP各时点比较差异均有统计学意义(P0.05),治疗组各时间点与术前比较差异有统计学意义(P0.05),时间因素与各指标存在线性关系与交互作用结果差异有统计学意义(P0.01)。功能指标方面,治疗组与对照组比较,RIMP、RVEF、TAPSE、FAC术后各时间点比较差异有统计学意义(P0.05),治疗组各时间点与术前比较差异有统计学意义(P0.05),时间因素与各指标存在线性关系与交互作用结果差异有统计学意义(P0.01)。结论:封堵术后患者右房、右室逐渐缩小,右心室功能逐渐恢复,因观察时间较短,其稳定性难以评估,需要更长时间的观察;非手术患者右心结构与功能缓慢变差,应及早治疗。
[Abstract]:Objective: to evaluate the long-term clinical effect of ASD after transcatheter closure of atrial septal defect (ASD) by echocardiography.Methods: a prospective cohort study was conducted in 70 patients.In the treatment group, 48 cases were treated by blocking operation, and 22 cases in the control group were treated by routine therapy.The changes of structure and function of right atrium and right ventricle were evaluated by transthoracic echocardiography before operation and 1 year after operation.Results: structurally,娌荤枟缁勪笌瀵圭収缁勬瘮杈，

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