针药并举治疗腰椎管狭窄对其影像学指标、炎性因子的影响分析

发布时间：2018-04-06 04:20

本文选题：中药汤剂　切入点：电针　出处：《中华中医药学刊》2017年04期

【摘要】：目的:探讨采用自拟中药汤剂与电针联合治疗腰椎管狭窄患者临床疗效,并观察其对患者炎症因子及腰椎管狭窄程度的影响。方法:回顾性分析医院2012月1月—2016年10月65例腰椎管狭窄患者临床诊治资料,其中以电针治疗者纳入对照组32例;以电针联合医院自拟中药汤剂治疗者纳入治疗组33例。采用影像学手段评价两组狭窄节段椎管矢状径与硬膜囊面积,抽取两组治疗前后空腹下血液,并采用酶联免疫吸附法检测其炎症指标(白细胞介素-1α-IL-1α,肿瘤坏死因子α-TNF-α),采用视觉模拟法(VAS)评价其治疗前、后疼痛程度,统计两组临床疗效及安全性。结果:治疗组治疗后IL-1α、TNF-α水平分别为(8.11±3.17)ng/L、(17.18±3.72)ng/L明显低于对照组(10.45±4.21)ng/L、(20.22±3.96)ng/L,P0.05,两组治疗后IL-1α、TNF-α水平均较治疗前明显下降,P0.05。治疗组治疗后狭窄节段椎管矢状径与硬膜囊面积、疼痛程度均较治疗前明显改善,且治疗组改善程度较对照组更显著,P0.05。治疗组治疗优良率90.91%,明显高于对照组68.75%,P0.05。治疗期间未见明显不良反应。结论:采用中药汤剂与电针联合治疗腰椎管狭窄患者可有利于减轻其炎症水平,加速其康复。
[Abstract]:Objective: to explore the clinical effect of self-made traditional Chinese medicine decoction and electroacupuncture on lumbar spinal canal stenosis, and to observe its effect on inflammatory factors and the degree of lumbar spinal stenosis.Methods: the clinical data of 65 patients with lumbar spinal stenosis in our hospital from January 2012 to October 2016 were retrospectively analyzed. Among them, 32 cases were treated with electroacupuncture and 33 cases were treated with traditional Chinese medicine decoction prepared by electroacupuncture United Hospital.The sagittal diameter and the area of dural sac were evaluated by imaging method in two groups.The inflammatory indexes (interleukin-1 伪 -IL-1 伪, tumor necrosis factor 伪 -TNF- 伪) were detected by enzyme-linked immunosorbent assay (Elisa), and the degree of pain before and after treatment was evaluated by visual simulation method. The clinical efficacy and safety of the two groups were counted.Results: after treatment, the levels of IL-1 伪 -TNF- 伪 in the treatment group were 8.11 卤3.17 ng / L and 17.18 卤3.72)ng/L, respectively, which were significantly lower than those in the control group (10.45 卤4.21 ng / L, 20.22 卤3.96 ng / L P 0.05). After treatment, the levels of IL-1 伪 TNF- 伪 in both groups were significantly lower than those before treatment (P 0.05).The sagittal diameter and dural sac area and pain degree in the treatment group were significantly improved than those before treatment, and the improvement degree in the treatment group was more significant than that in the control group (P 0.05).The excellent and good rate of treatment in the treatment group was 90.91, which was significantly higher than that in the control group (68.75) (P 0.05).There was no obvious adverse reaction during treatment.Conclusion: the treatment of lumbar spinal stenosis with traditional Chinese medicine decoction and electroacupuncture can reduce the inflammatory level and accelerate the recovery.
【作者单位】：丽水市中心医院庆元分院;衢州市人民医院;
【分类号】：R681.5

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