抗生素珠链植入联合VSD治疗对慢性骨髓炎患者红细胞免疫功能和生活质量的影响

发布时间：2018-04-19 02:22

本文选题：慢性骨髓炎 + 抗生素　；参考：《山东医药》2017年37期

【摘要】：目的探讨抗生素珠链植入联合负压封闭引流技术(VSD)治疗对慢性骨髓炎患者红细胞(RBC)免疫功能和生活质量的影响。方法将58例慢性骨髓炎患者根据随机数字表法分为对照组和观察组各29例。对照组采用抗生素灌洗加常规引流治疗,观察组采用抗生素珠链植入联合VSD治疗。治疗后9个月对比两组总有效率、复发率;治疗前及治疗后3个月检测RBC免疫功能指标,采用健康测量量表对两组生存质量进行评分。结果观察组总有效率高于对照组,复发率低于对照组(P均0.05)。治疗后两组RBC免疫功能指标水平及生存质量评分均较治疗前升高(P均0.05),且观察组高于对照组(P均0.05)。结论抗生素珠链植入联合VSD治疗能够增强慢性骨髓炎患者RBC免疫功能,提高其生活质量。
[Abstract]:Objective to investigate the effects of antibiotic beads implantation combined with negative pressure blocking drainage (VSD) on the immune function and quality of life of erythrocytes in patients with chronic osteomyelitis.Methods 58 patients with chronic osteomyelitis were randomly divided into control group (n = 29) and observation group (n = 29).The control group was treated with antibiotic lavage plus routine drainage, while the observation group was treated with antibiotic bead chain implantation and VSD.After 9 months of treatment, the total effective rate and recurrence rate of the two groups were compared, the immune function of RBC was measured before treatment and 3 months after treatment, and the quality of life of the two groups was evaluated by health measurement scale.Results the total effective rate in the observation group was higher than that in the control group, and the recurrence rate was lower than that in the control group (P < 0.05).After treatment, the level of RBC immune function and the quality of life score in the two groups were higher than those before treatment (P 0.05), and the observation group was higher than the control group (P 0.05).Conclusion antibiotic bead chain implantation combined with VSD can enhance RBC immune function and improve quality of life in patients with chronic osteomyelitis.
【作者单位】：山东省交通医院;山东省女子监狱医院;
【分类号】：R681.2

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