正中神经电刺激对脑外伤后昏迷促醒治疗的参数研究

发布时间：2018-04-19 17:15

本文选题：脑外伤 + 昏迷　；参考：《中国康复理论与实践》2017年02期

【摘要】：目的探讨正中神经电刺激促进脑外伤后昏迷患者觉醒的最佳治疗参数。方法 2013年至2015年,本院161例颅脑外伤患者随机分为对照组(n=40)、实验1组(n=41)、实验2组(n=39)和实验3组(n=41)。对照组使用常规促醒方法;实验组在此基础上加用正中神经电刺激治疗。参数设置:实验1组200μs,30 Hz;实验2组200μs,100 Hz,实验3组200μs,50 Hz。每次60min,每天2次,30 d为1个疗程,共治疗3个疗程。治疗前、治疗30 d和治疗结束后分别比较格拉斯哥昏迷量表(GCS)和改良国际昏迷恢复量表(CRS-R)得分。结果治疗30 d和治疗后,各组在GCS评分、CRS-R评分、治疗次数、清醒人数、昏迷时间有非常显著性差异(P0.01);实验各组均优于对照组(P0.05),实验1组与实验2组间无显著性差异(P0.05),实验3组优于实验1组和实验2组(P0.05)。结论正中神经电刺激治疗参数为波宽200μs、频率50 Hz时,能更好更早地促进患者的苏醒。
[Abstract]:Objective to explore the best therapeutic parameters of median nerve electrical stimulation (MNFS) for promoting the awakening of coma patients after brain injury.Methods from 2013 to 2015, 161 patients with craniocerebral trauma in our hospital were randomly divided into control group (n = 40), group 1 (n = 41), group 2 (n = 39) and group 3 (n = 41).The control group was treated with conventional arousal method, and the experimental group was treated with median nerve stimulation.The parameters were set up as follows: experimental group 1 (200 渭 s) 30 Hz, experiment 2 (200 渭 s) 100 Hz, experiment 3 (200 渭 s) 50 Hz.Each time 60 minutes, twice a day for 30 days as a course of treatment, a total of 3 courses of treatment.The scores of Glasgow coma scale (Glasgow coma scale) and modified International coma recovery scale (CRS-RV) were compared 30 days before treatment and 30 days after treatment.Results after 30 days of treatment and after treatment, the GCS score, the number of times of treatment, and the number of awake persons were evaluated in each group.There was significant difference in the duration of coma (P 0.01), the difference between the experimental group and the control group was better than that in the control group (P 0.05), but there was no significant difference between the experimental group 1 and the experimental group 2 (P 0.05), and the third group was better than the group 1 and the group 2 (P 0.05).Conclusion when the median nerve electrical stimulation is 200 渭 s in width and 50 Hz in frequency, it can promote the recovery of patients better and earlier.
【作者单位】：南昌大学第一附属医院康复医学科;
【基金】：国家自然科学基金项目(No.81260295) 江西省自然科学基金项目(No.20132BAB205063) 江西省卫生厅科技计划项目(No.20131026)
【分类号】：R651.15

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