经口内镜下肌切开术治疗贲门失弛缓症临床疗效和并发症的分析

发布时间：2018-04-20 19:40

本文选题：贲门失弛缓症 + 经口内镜下肌切开术　；参考：《中国内镜杂志》2016年07期

【摘要】：目的探讨经口内镜下肌切开术(POEM)治疗贲门失弛缓症(AC)的临床疗效和并发症。方法对2013年1月-2015年1月该院消化内镜中心的38例AC患者进行POEM治疗,观察手术相关并发症和胃食管反流情况,并对比分析治疗前后贲门失弛缓症临床症状评分系统(ECKARDT)评分和食管下段括约肌(LES)压力变化。结果 38例均成功实施POEM手术,无1例出现与POEM相关的严重并发症,出血、气体相关并发症均保守治疗成功。术后随访时间10.4个月(9~12个月),所有患者症状缓解,ECKARDT评分平均分从术前的8.7分降至术后的1.2分(P0.01),食管括约肌压力明显降低,平均压从术前的(33.40±11.80)mm Hg下降至术后的(13.50±4.30)mm H(g P0.01),气体相关并发症6例(15.78%),食管反流总发生率为23.68%(9/38)。结论 POEM用于AC的治疗是安全、有效的,并且具有较好的远期疗效。
[Abstract]:Objective to investigate the clinical effect and complications of poemonotomy via oral endoscope in the treatment of achalasia. Methods from January 2013 to January 2015, 38 patients with AC were treated with POEM. The complications associated with operation and gastroesophageal reflux were observed. The clinical symptom score of achalasia and the pressure of lower esophageal sphincter were compared before and after treatment. Results POEM was performed successfully in all the 38 cases. No serious complications associated with POEM were found in all cases. Bleeding and gas related complications were all treated conservatively. The follow-up time was 10.4 months from 9 to 12 months. The average score of ECKARDT in all patients was decreased from 8.7 before operation to 1.2 before operation (P 0.01), and the esophageal sphincter pressure decreased significantly. The mean pressure was decreased from 33.40 卤11.80)mm Hg before operation to 13.50 卤4.30)mm Hg P 0.01 after operation. There were 6 cases of gas-related complications, and the total incidence of esophageal regurgitation was 23.68% / 38%. Conclusion POEM is safe, effective and effective in the treatment of AC.
【作者单位】：南华大学第一附属医院消化内科;
【分类号】：R655.4

【相似文献】