血必净注射液对重症创伤患者炎症反应的抑制作用

发布时间：2018-05-06 22:00

本文选题：血必净注射液 + 重症创伤患者　；参考：《临床医药文献电子杂志》2016年44期

【摘要】：目的研究对重症创伤患者给予血必净注射液后对全身炎症反应的抑制作用。方法选取2010年1月~2014年1月我院收治的重症创伤类患者200例,将其随机分为对照组和观察组,各100例。对照组给予常规治疗,观察组在常规治疗基础上再给予血必净注射液治疗。两组患者治疗前后对肿瘤坏死因子-α,白细胞介素-6,白细胞介素-8的水平情况进行检测,并对比分析两组患者各项指标的差别及病死率情况。结果对比治疗前后的各种指标,发现两组肿瘤坏死因子-α,白细胞介素-6,白细胞介素-8的水平情况均有所下降,且对照组的下降幅度明显小于观察组,差异有统计学意义(P0.05);观察组的感染率及病死率明显低于对照组,差异有统计学意义(P0.05)。结论对重症创伤患者应用血必净注射液可以有效地抑制炎症因子,减少死亡率,降低感染率,值得临床推广应用。
[Abstract]:Objective to study the inhibitory effect of Xuebijing injection on systemic inflammation in patients with severe trauma. Methods 200 patients with severe trauma from January 2010 to January 2014 were randomly divided into control group and observation group with 100 cases each. The control group was treated with routine therapy, the observation group was treated with Xuebijing injection on the basis of routine treatment. The levels of tumor necrosis factor- 伪, interleukin-6 and interleukin-8 were detected before and after treatment in two groups. Results compared with the indexes before and after treatment, the levels of tumor necrosis factor- 伪, interleukin-6 and interleukin-8 in the two groups were all decreased, and the decrease in the control group was significantly lower than that in the observation group. The infection rate and mortality in the observation group were significantly lower than those in the control group (P 0.05). Conclusion Xuebijing injection can effectively inhibit inflammatory factors, reduce mortality and reduce infection rate in patients with severe trauma.
【作者单位】：元氏县医院骨科;
【分类号】：R641

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