帕瑞昔布用于腹腔镜胆囊切除术后疼痛的疗效观察

发布时间：2018-05-13 05:35

本文选题：腹腔镜胆囊切除术 + 帕瑞昔布　；参考：《重庆医科大学》2017年硕士论文

【摘要】：目的:探索帕瑞昔布用于腹腔镜胆囊切除术后的疼痛疗效评价。方法:选取择期行腹腔镜胆囊切除术的患者120例,随机分为A组实验组(n=60)术后应用镇痛泵的同时,并在手术结束后2、6、12、24h静注帕瑞昔布40毫克;B组对照组(n=60)术后使用镇痛泵的同时,并在手术结束后2、6、12、24h给予10毫升生理盐水静注。A组和B组均用视觉模拟评分法对两组手术后当天、手术后第1天、手术后第2天进行疼痛评分,并记录术后住院天数、肛门排气时间、开始下床活动时间、夜间睡眠时间、不良反应等。结果:A组手术后当天、手术后第1天、手术后第2天疼痛评分均低于B组(P0.05)。两组术后住院天数比较,无显著性差异(P=0.529)。A组肛门排气时间、开始下床活动时间均低于B组(P0.05)。A组手术后当天、手术后第1天夜间睡眠时间高于B组(P0.05)。A组恶心、呕吐的发生率低于B组(P0.05)。结论:腹腔镜胆囊切除术后使用帕瑞昔布能明显减少患者的术后疼痛,提高术后睡眠时间,促进患者的功能恢复,有效减少不良反应的发生。
[Abstract]:Objective: to evaluate the effect of paroxib on pain after laparoscopic cholecystectomy. Methods: one hundred and twenty patients undergoing laparoscopic cholecystectomy were randomly divided into two groups: group A (group A) were treated with analgesic pump at the same time as the experimental group (n = 60), and the control group (n = 60) received intravenous injection of paroxib 40 mg / L for 24 h after operation. The patients in group A and group B were given 10 ml saline intravenously for 24 hours after operation. The pain scores were evaluated by visual analogue scoring method on the day of operation, the first day after operation, and the second day after operation, and the days of postoperative hospitalization were recorded. Anal exhaust time, time to get out of bed, night sleep time, adverse reactions, etc. Results the scores of pain in group A were lower than those in group B on the day of operation, the first day after operation and the second day after operation. There was no significant difference in postoperative hospitalization days between the two groups. There was no significant difference between group A and group A in anal exhaust time, and the time of getting out of bed was lower than that of group B (P 0.05). The first day after operation, the sleep time of group A was higher than that of group B (P 0.05), and that of group A was higher than that of group A (P 0.05), and that of group A was lower than that of group A (P 0.05). The incidence of vomiting was lower than that of group B (P 0.05). Conclusion: the use of paroxib after laparoscopic cholecystectomy can significantly reduce postoperative pain, improve postoperative sleep time, promote the functional recovery of patients, and effectively reduce the occurrence of adverse reactions.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R614

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