强直性脊柱炎全髋关节置换后隐性失血的危险因素分析

发布时间：2018-05-14 18:31

  本文选题：脊柱炎 + 强直性　； 参考：《中国组织工程研究》2017年11期

【摘要】：背景:全髋关节置换是治疗强直性脊柱炎累及髋关节破坏的有效措施,强直性脊柱炎患者全髋关节置换后有不同程度的贫血,而隐性失血在全髋关节置换围手术期失血量占有较大比例,影响关节功能的恢复。目的:分析强直性脊柱炎髋关节受累患者接受全髋关节置换后隐性失血的危险因素。方法:人工全髋关节置换治疗的60例(70髋)强直性脊柱炎累及髋关节的患者,平均年龄35.12岁。根据Gross方程计算隐性失血量,收集和分析手术时间、血沉、C-反应蛋白、体质量指数、是否骨质疏松、强直性脊柱炎髋关节放射指数、异体输血量等对患者全髋关节置换后隐性失血的影响,并按隐性失血量分为高隐性失血组(≥480 m L)和低隐性失血组(480 mL),通过单因素相关分析及多因素Logistic回归分析(SPSS17.0)影响强直性脊柱炎患者初次全髋关节置换术后高隐性失血的危险因素。结果与结论:(1)患者初次全髋关节置换后隐性失血量为(737.76±419.18)mL,总失血量为(1 312.83±487.41)mL,隐性失血占总失血量的51.48%。高隐性失血组41髋,低隐性失血组29髋,比例为41∶29;(2)单因素相关分析结果显示手术时间、强直性脊柱炎髋关节放射指数、是否骨质疏松、异体输血量、血红蛋白下降量与高隐性失血显著相关;(3)多因素Logistic回归分析结果显示强直性脊柱炎髋关节放射指数、异体输血量、血红蛋白下降量与高隐性失血显著相关;(4)结果说明,隐性失血量是强直性脊柱炎患者初次全髋关节置换后总失血量的重要组成部分,强直性脊柱炎髋关节放射指数、异体输血量、血红蛋白下降量是高隐性失血的危险因素。
[Abstract]:Background: total hip replacement is an effective treatment for ankylosing spondylitis involving hip destruction. Patients with ankylosing spondylitis have different degrees of anemia after total hip replacement. Recessive blood loss accounts for a large proportion of total hip replacement perioperative blood loss, affecting the recovery of joint function. Objective: to analyze the risk factors of recessive blood loss after total hip replacement in patients with ankylosing spondylitis. Methods: total hip replacement was performed in 60 patients with ankylosing spondylitis. The average age was 35.12 years. According to Gross equation, the recessive blood loss was calculated, and the operative time, ESR C-reactive protein, body mass index, osteoporosis, ankylosing spondylitis hip radioactivity index were collected and analyzed. Effects of allogeneic blood transfusion on recessive blood loss after total hip replacement, The patients were divided into high recessive bleeding group (鈮，

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