糖尿病专用肠内营养混悬液康全力对肝脏术后患者血糖的影响

发布时间：2018-05-18 22:26

本文选题：肝脏手术 + 肠内营养　；参考：《中国医院药学杂志》2017年15期

【摘要】：目的:观察糖尿病专用肠内营养混悬液应用于肝脏术后伴发应激性高血糖的患者,对其血糖的影响。方法:将116例肝脏手术后伴发应激性高血糖患者随机分为2组,观察组给予糖尿病专用肠内营养混悬液(康全力,TPF-DM),对照组给予普通肠内营养混悬液(能全力,TPF),使用动态血糖监测系统(CGMS)记录患者血糖,为时18 d,比较2组患者24 h血糖波动幅度(24 h MAGE)、餐后2 h血糖(2hPG)、日均胰岛素用量、CGMS血糖值在各范围所占百分比。结果:观察组和对照组24 h MBG(mmol·L-1)分别为(8.38±1.59)和(9.10±1.63),2hPG(mmol·L-1)分别为(9.35±1.17)和(12.36±2.65),日均胰岛素用量(u)分别为(15.2±11.3)和(37.6±12.0)。观察组的24h MBG、2hPG、日均胰岛素用量优于对照组,差异有统计学意义(P0.05);观察组与对照组比较CGMS血糖值在各范围所占百分比差异有统计学意义(P0.05)。结论:糖尿病专用肠内营养混悬液的使用可以降低肝脏术后伴发应激性高血糖患者的24h MBG及2hPG,减少胰岛素的用量,对控制术后应激性高血糖是有益的。
[Abstract]:Aim: to observe the effect of diabetic enteral nutrition suspension on blood glucose in patients with stress hyperglycemia after liver operation. Methods: 116 patients with stress hyperglycemia after liver operation were randomly divided into two groups. The observation group was given special enteral nutrition suspension of diabetes mellitus (Kangzhuo TPF-DMN), the control group was given general enteral nutrition suspension (TPFN), and the blood glucose was recorded by dynamic blood glucose monitoring system (CGMSs). For 18 days, the fluctuation range of 24 h blood glucose in the two groups was compared with that of 24 h MAGEN, 2 h postprandial blood glucose and 2 h PGN, and the percentage of CGMs in each range. Results: 24 h MBG(mmol L ~ (-1) in the observation group and the control group were 8.38 卤1.59) and 9.10 卤1.63 MBG(mmol / L ~ (-1), respectively, which were 9.35 卤1.17) and 12.36 卤2.65m, respectively. The daily average insulin dosage was 15.2 卤11.3) and 37.6 卤12.0%, respectively. Compared with the control group, the daily insulin dosage of the observation group was significantly higher than that of the control group (P 0.05), and the percentage of blood glucose of CGMS in the observation group was significantly higher than that in the control group (P 0.05). Conclusion: the use of special enteral nutrition suspension for diabetes can reduce 24 hours MBG and 2 hPGs of patients with stress hyperglycemia after liver operation, and reduce the dosage of insulin, which is beneficial to control stress hyperglycemia after operation.
【作者单位】：天津市职业病防治院药剂科;首都医科大学附属北京佑安医院肝胆外科;天津市职业病防治院急诊科;
【分类号】：R657.3

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