远端胰腺切除术后胰瘘发生的危险因素分析

发布时间：2018-05-28 04:04

本文选题：胰腺切除术 + 胰腺瘘　；参考：《中国普通外科杂志》2017年03期

【摘要】：目的:探讨影响远端胰腺切除术后胰瘘发生的相关性因素。方法:回顾2010年2月—2016年5月所实施的100例远端胰腺切除术患者临床资料,对相关因素进行单因素与多因素分析。结果:100例患者中32例(32%)发生术后胰瘘,包括A级胰瘘(无临床意义)18例(18%),有临床意义的胰瘘14例(14%),其中B级胰瘘8例,C级胰瘘6例。单因素分析中,高体质量指数(≥25kg/m~2)与术后胰瘘发生有关(χ~2=4.128,P=0.042),但与有临床意义的胰瘘发生无关(χ~2=1.545,P=0.214),软胰腺质地与胰瘘及有临床意义的胰瘘发生均明显有关(χ~2=4.569,P=0.033;χ~2=11.374,P=0.001)。多因素分析中软胰腺质地是胰瘘及有临床意义的胰瘘发生的唯一独立危险因素(OR=2.476,P=0.043;OR=8.012,P=0.003)。结论:胰腺质地是远端胰腺切除术后胰瘘发生的重要影响因素,对于胰腺质地软者,应采取积极防治措施。
[Abstract]:Objective: To investigate the related factors affecting the occurrence of pancreatic fistula after distal pancreatectomy. Methods: To review the clinical data of 100 patients with distal pancreatectomy from February 2010 to May 2016, and to analyze the related factors by single factor and multi factor analysis. Results: 32 cases (32%) of 100 patients had postoperative pancreatic fistula, including a grade pancreatic fistula (no clinical intention). 18 cases (18%), 14 cases of pancreatic fistula in clinical significance (14%), including 8 cases of B pancreatic fistula and 6 cases of C pancreatic fistula. In single factor analysis, high body mass index (> 25kg/m~2) was associated with postoperative pancreatic fistula (x ~2=4.128, P=0.042), but there was no clinical significance of pancreatic fistula (x ~2=1.545, P=0.214), soft pancreas texture and pancreatic fistula and clinically significant pancreatic fistula. The texture of the soft pancreas is the only independent risk factor for pancreatic fistula and the clinical significance of pancreatic fistula (OR=2.476, P=0.043; OR=8.012, P=0.003) in multifactor analysis. Conclusion: the quality of the pancreas is an important factor of pancreatic fistula after the distal pancreatic resection, and the quality of the pancreas is of the texture of the pancreas. The soft people should take active measures to prevent and cure them.
【作者单位】：浙江省安吉县人民医院外二科;
【分类号】：R657.5

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