全膝关节置换术后假体周围感染的病原学分析

发布时间：2018-05-30 22:16

本文选题：全膝关节置换术 + 假体周围感染　；参考：《中国骨与关节损伤杂志》2016年11期

【摘要】：目的分析全膝关节置换术后假体周围感染患者的病原菌构成及药敏结果,为假体周围感染的诊治提供参考。方法收集自2008-01—2014-12诊治的全膝关节置换术后假体周围感染28例,对全膝关节置换术后假体周围感染标本培养的病原菌及药敏结果进行统计分析。结果 28例中共检出病原菌19株,病原菌检出率为67.86%。19株病原菌包括革兰阳性球菌12株(63.16%),革兰阴性杆菌5株(26.32%),分支杆菌属及奴卡菌属各1株。革兰阳性球菌对万古霉素、利耐唑胺、米诺环素等药物敏感率高。革兰阴性杆菌对亚胺培南、美罗培南、舒普深等药物敏感率高。结论全膝关节置换术后应积极预防假体周围感染,一旦发生假体周围感染,应多次行细菌培养与药敏试验,及时应用敏感抗生素。
[Abstract]:Objective to analyze the pathogenic bacteria composition and drug sensitivity of patients with periprosthetic infection after total knee arthroplasty, and to provide reference for the diagnosis and treatment of periprosthetic infection. Methods Twenty-eight cases of periprosthetic infection after total knee arthroplasty were collected from January to December 2014. The results of pathogenic bacteria and drug sensitivity in the culture of periprosthetic infection specimens after total knee arthroplasty were statistically analyzed. Results A total of 19 strains of pathogenic bacteria were detected in 28 cases. The detectable rate of pathogens was 67.86.19 strains including 12 Gram-positive cocci, 5 Gram-negative bacilli, 1 Mycobacterium and 1 Neucella, respectively. Gram-positive cocci were sensitive to vancomycin, ribazolamine and minocycline. Gram-negative bacilli are highly sensitive to imipenem, meropenem and sulpshen. Conclusion the periprosthetic infection should be prevented actively after total knee arthroplasty. In case of periprosthetic infection, bacterial culture and drug sensitivity test should be carried out many times, and sensitive antibiotics should be used in time.
【作者单位】：青岛市中心医院骨外科;青岛大学附属医院骨外科;
【基金】：山东省科技攻关项目(2010GWZ20225)
【分类号】：R687.4

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