肠内营养联合益生菌对老年颅脑外伤患者营养状况和胃肠功能的影响

发布时间：2018-06-03 05:02

本文选题：颅脑外伤 + 益生菌　；参考：《中国老年学杂志》2017年14期

【摘要】：目的探讨肠内营养联合益生菌对老年颅脑外伤患者营养状况和胃肠功能的影响。方法老年颅脑外伤患者126例按照随机数字表法分为观察组和对照组,每组63例,对照组入院24 h内开始肠内营养支持,观察组在对照组的基础上加入益生菌,比较两组治疗情况、肠胃动力情况、营养状况及肠黏膜屏障功能。结果治疗15 d时,两组格拉斯哥昏迷量表(GCS)评分均提高,且观察组显著高于对照组(P0.05);观察组达目标喂养时间、重症监护时间、住院时间、首次排便时间和胃肠道反应发生率均显著短于或低于对照组(P0.05);治疗21 d时,观察组血清白蛋白水平显著高于治疗前和对照组,而空腹血糖、D-乳酸、降钙素原(PCT)水平显著低于治疗前和对照组(均P0.05)。结论与单纯的肠内营养支持治疗比较,肠内营养联合益生菌治疗老年颅脑外伤可以进一步改善患者肠胃功能,提高机体营养状况。
[Abstract]:Objective to investigate the effects of enteral nutrition combined with probiotics on nutritional status and gastrointestinal function in elderly patients with craniocerebral trauma. Methods 126 elderly patients with craniocerebral trauma were randomly divided into observation group (n = 63) and control group (n = 63). The control group received enteral nutrition support within 24 hours after admission. The observation group was supplemented with probiotics on the basis of the control group. The therapeutic conditions, gastrointestinal motility, nutritional status and intestinal mucosal barrier function were compared between the two groups. Results after 15 days of treatment, the Glasgow coma scale (GCSs) scores in both groups were significantly higher than those in the control group (P 0.05), and the feeding time, intensive care time and hospitalization time in the observation group were significantly higher than those in the control group. The first defecation time and the incidence of gastrointestinal reaction were significantly shorter than or lower than those of the control group (P 0.05), the serum albumin level in the observation group was significantly higher than that in the control group and before treatment, while the fasting blood glucose and D-lactic acid levels in the observation group were significantly higher than those in the control group after 21 days of treatment. The level of procalcitonin PCT was significantly lower than that before treatment and control group (P 0.05). Conclusion compared with enteral nutrition alone, enteral nutrition combined with probiotics can further improve the gastrointestinal function and nutritional status of elderly patients with craniocerebral trauma.
【作者单位】：滨州医学院附属医院神经外科;
【分类号】：R651.15

【参考文献】