3D打印技术在颅内动静脉畸形血管内介入治疗中的初步应用

发布时间：2018-06-16 00:01

本文选题：颅内动静脉畸形 + D打印　；参考：《中国脑血管病杂志》2016年01期

【摘要】：目的探讨3D打印技术在指导颅内动静脉畸形(AVM)血管内介入治疗中的临床应用价值。方法贯序交替选取2015年2月至5月广东省人民医院神经外科进行血管内介入治疗的AVM患者10例,其中5例为对照组,5例为进行3D打印模型试验组。对试验组5例AVM患者采用256层螺旋CT薄层增强扫描或3D-DSA旋转成像,提取检查结果的DICOM原始数据,应用薄层数据扫描获取5例AVM患者三维数据,通过Mimics 14.01软件进行数字化数据提取和重建,并按1∶1比例进行3D打印,获得实体模型。应用AVM实体模型指导与患者及其家属的术前谈话及手术方案设计,并与对照组结果进行对比。结果 3D打印模型试验组术前谈话时间(10.2±0.8)min较对照组术前谈话时间(15.0±1.3)min显著缩短,差异有统计学意义(P0.01);试验组患者及其家属满意度评分显著高于对照组[(9.3±0.6)分比(8.1±0.3)分,P0.01],试验组术中造影后至手术实施时间较对照组显著缩短[(5.7±0.4)min比(10.5±1.6)min,P0.01]。无一例手术相关并发症。结论 3D打印模型可以帮助术者更加直观地了解畸形团空间构筑学特征,指导术者进行手术方案的制定,同时应用3D打印实体模型可提高与AVM患者术前谈话效率及患者满意度。
[Abstract]:Objective to evaluate the clinical value of 3D printing in the guidance of intra-vascular interventional therapy for intracranial AVM (Arteriovenous malformation). Methods from February to May 2015, 10 patients with AVM underwent endovascular interventional therapy in neurosurgery department, Guangdong Provincial people's Hospital, including 5 patients in the control group and 5 patients in the 3D printing model group. In the test group, five patients with AVM were examined with 256-slice spiral CT thin slice enhanced scanning or 3D-DSA rotation imaging. The original DICOM data were extracted from the results of the examination, and the 3D data of 5 patients with AVM were obtained by thin layer data scanning. The digitized data is extracted and reconstructed by imics 14.01, and 3D printing is carried out according to 1:1 scale, and the solid model is obtained. The AVM solid model was used to guide the preoperative conversation and the design of the surgical scheme with the patients and their families, and the results were compared with those of the control group. Results the time of preoperative conversation in 3D print model group was significantly shorter than that in control group (10. 2 卤0.8)min, 15. 0 卤1.3)min, P < 0. 05). The scores of satisfaction of patients and their families in the trial group were significantly higher than those in the control group [9.3 卤0.6 vs 8.1 卤0.3, P0.01], and the time from the operation to the operation in the trial group was significantly shorter than that in the control group [5.7 卤0.4)min vs 10.5 卤1.6min, P0.01]. No surgical complications were found. Conclusion 3D printing model can help the operators to understand the spatial architecture characteristics of the deformities more intuitively, and guide the operation plan. Meanwhile, the 3D printing entity model can improve the efficiency and satisfaction of the patients with AVM before operation.
【作者单位】：广东省人民医院(广东省医学科学院)神经外科;南方医科大学基础医学院解剖学教研室;
【基金】：广东省科技计划项目(2013B021B00179) 广州市科技计划项目(2014J4100042)
【分类号】：R651.12

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