后路短节段固定联合植骨治疗胸腰椎爆裂性骨折的Meta分析

发布时间：2018-06-20 04:07

  本文选题：随机对照试验 + 胸腰椎骨折　； 参考：《颈腰痛杂志》2015年02期

【摘要】：目的系统评价植骨与否对后路短节段固定治疗胸腰椎爆裂性骨折的效果。方法由两人分别计算机检索MEDLINE(1966-2014.7),ELSEVIER,Springerlink和Google Scholar等数据库,收集比较后路短节段固定植骨或不植骨治疗胸腰椎爆裂性骨折的随机对照试验进行Meta分析,并评价纳入研究的方法学质量,采用Cochrane协作网提供的统计学软件Rev Man5.3及偏倚风险评估标准进行分析。结果共纳入符合标准的随机对照试验4篇,包含198位患者。所有纳入研究的基本特征较为一致,研究发现后路短节段固定治疗胸腰椎骨折效果满意,植骨与非植骨在术后的临床、影像学结果及内固定失败等方面没有显著统计学差异。非植骨融合组在手术时间、术中出血量、避免供骨区并发症等方面具有明显优势。结论短期结果显示同时行植骨融合对后路短节段固定治疗严格筛选的胸腰椎爆裂性骨折(LSC评分≤6)是没有必要的,但需要更多和更长时间的临床验证。
[Abstract]:Objective to evaluate the effect of bone graft on thoracolumbar burst fracture. Methods the databases of ELSEVIERN Springerlink and Google Scholar were searched by MEDLINE from June 1966-April 7, 2014.The data were collected and compared in a randomized controlled trial with or without bone graft for thoracolumbar burst fracture, and the quality of methodology was evaluated. The statistical software Rev Man5.3 provided by Cochrane Cooperative Network and the bias risk assessment criteria were used to analyze the results. Results A total of 4 randomized controlled trials including 198 patients were included. All the basic characteristics of the study were consistent. It was found that the treatment of thoracolumbar vertebrae fractures with posterior short segment fixation was satisfactory. There was no significant difference in the clinical, imaging results and internal fixation failure between bone graft and non-graft. The non-graft fusion group had obvious advantages in operation time, intraoperative bleeding volume, and avoiding complications in donor bone area. Conclusion the short term results showed that simultaneous bone graft fusion was not necessary for LSC score 鈮，

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