脾与残肝体积比和肝切除术后肝功能相关分析研究

发布时间：2018-07-05 15:11

  本文选题：原发性肝癌 + 肝功能试验　； 参考：《新疆医科大学》2015年硕士论文

【摘要】：目的：研究探讨脾与残肝体积比在肝切除手术后的肝脏储备功能的评估价值。应用肝脏三维重建软件IQQA-Liver(美国EDDA公司)和水侵法测量原发性肝癌肝切除术后残肝体积、脾脏体积,并计算出脾与残肝体积比,分析脾与残肝体积比和肝癌切除术后肝功能指标的相关性,了解脾与残肝体积对术后肝脏储备功能的影响,为临床医生在术前准确评估术后肝脏功能,避免肝癌切除术后肝功能衰竭的发生提供指导。方法：回顾性分析2012年2月至2013年6月共57例被我科诊断为实施手术治疗的肝硬化肝癌患者,应用肝脏三维重建软件IQQA-Liver和水侵法测量原发性肝癌肝切除术后残肝体积、脾脏体积,并计算出脾与残肝体积比,分析脾与残肝体积比与患者术后肝功能情况及住院时间的关系。结果：经过多元回归分析结果提示肝癌肝切除术后肝功能评分Child-Pugh与脾与残肝体积比有关。脾与残肝体积比值越小。其评分越低(t=7.731,P≈0.000),即肝脏储备功能越好。当脾与残肝体积比≤0.9时。患者中位住院时间为13 d(11-15 d)。当脾与残肝体积比0.9时,患者中位住院时间为21 d(14-28d)。两者的住院时间差异有统计学意义(P=0.000)。结论：脾与残肝体积比可以有效预测肝癌肝切除术后的肝脏储备功能,术前应制定详细的手术计划,估算残肝体积(脾与残肝体积比≤0.9),避免手术风险,减少术后肝功能损害的发生。
[Abstract]:Objective: to investigate the value of spleen to residual liver volume ratio in evaluating liver reserve function after hepatectomy. The residual liver volume and spleen volume after hepatectomy were measured by using IQQA-Liver (EDDA company) and water invasion method, and the volume ratio of spleen to remnant liver was calculated. To analyze the correlation between the volume ratio of spleen and remnant liver and the liver function index after hepatectomy, to understand the effect of spleen and residual liver volume on liver reserve function after hepatectomy, so as to evaluate the liver function accurately before and after hepatectomy. To avoid liver failure after hepatectomy provides guidance. Methods: from February 2012 to June 2013, 57 patients with liver cirrhosis diagnosed by our department as surgical treatment were analyzed retrospectively. The residual liver volume after hepatectomy was measured by IQQA-Liver and water invasion software. The volume ratio of spleen to remnant liver was calculated and the relationship between the volume ratio of spleen and residual liver and postoperative liver function and hospitalization time was analyzed. Results: the results of multiple regression analysis showed that Child-Pugh was related to the volume ratio of spleen to remnant liver after hepatectomy. The smaller the volume ratio of spleen to remnant liver was. The lower the score (t = 7.731 P 鈮，

本文编号：2100646