心脏外科术后患者深部胸骨切口感染的临床特征与病原菌分布及耐药性研究

发布时间：2018-07-25 20:20

【摘要】：目的探讨心脏外科术后患者深部胸骨切口感染的临床特征、病原菌分布及耐药性的情况,为临床诊疗提供理论依据。方法回顾性分析医院收治的心脏外科手术后深部胸骨切口感染患者69例;对比不同临床分型的深部胸骨切口感染患者的临床表现、实验室检查以及影像学检查结果;分析深部胸骨切口感染的病原菌分布及主要病原菌的耐药性情况。结果Ⅲ型深部胸骨切口感染体温≥38℃的比例、自发性疼痛的比例、白细胞计数10×109/L的比例均显著低于Ⅰ型和Ⅱ型深部胸部切口感染(P0.05);Ⅲ型深部胸骨切口感染术口裂开或见脓性分泌物的比例显著低于Ⅱ型深部胸骨切口感染(P0.05);Ⅲ型深部胸骨切口感染低蛋白血症的比例显著低于Ⅰ型深部胸骨切口感染(P0.05);本研究共培养出病原菌76株,其中,革兰阴性菌42株(55.26%),革兰阳性菌30株(39.47%),真菌4株(5.26%);铜绿假单胞菌对头孢他啶、头孢吡肟、亚胺培南和美罗培南均有较高的敏感性,耐药率均为16.67%;鲍曼不动杆菌对临床常用的抗菌药物均表现出高度的耐药性;金黄色葡萄球菌和表皮葡萄球菌对青霉素G和克拉霉素均表现出高度的耐药性,而对替加环素、利奈唑胺和万古霉素均敏感,耐药率均为0.00%。结论心脏外科术后应密切观察患者的病情变化,及早发现深部胸骨切口感染并规范应用抗菌药物,改善患者的预后。
[Abstract]:Objective to investigate the clinical characteristics, distribution of pathogens and drug resistance of deep sternum incision infection after cardiac surgery, and to provide theoretical basis for clinical diagnosis and treatment. Methods Sixty-nine patients with deep sternal incision infection after cardiac surgery were retrospectively analyzed, and the clinical manifestations, laboratory and imaging findings of patients with deep sternal incision infection of different clinical types were compared. To analyze the distribution of pathogenic bacteria and drug resistance of main pathogens in deep sternal incision infection. Results the proportion of body temperature 鈮，

本文编号：2144970