乌蔹莓膏联合负压辅助愈合治疗系统对高位复杂性肛瘘术后创面愈合的影响

发布时间：2018-07-25 20:59

【摘要】：目的探讨乌蔹莓膏联合负压辅助愈合系统(VAC)治疗高位复杂性肛瘘术后创面愈合的效果。方法选取选取2016年1-10月该院收治的高位复杂性肛瘘术后患者72例,采用随机数字表法将其分为对照组和观察组,每组36例。对照组给予术后常规创面消毒和外敷凡士林油纱条覆盖创面,再以敷料固定;观察组术后创面常规消毒,先以乌蔹莓膏涂敷创面一层,涂药后创面覆盖隔离垫,再给VAC治疗,直至出院为止,比较两组创面愈合速度、疼痛程度、创面细菌检测率及半年内复发率。结果观察组术后第10天创面愈合速度[(45.7±2.1)%vs.(22.1±1.6)%]、术后第15天创面愈合速度[(76.2±1.7)%vs.(39.7±1.5)%]、术后第10天细菌检出率(8.3%vs.44.4%)、术后6个月复发率(2.7%vs.16.7%)均优于对照组,差异均有统计学意义(P0.05);观察组术后第7天疼痛评估较对照组轻,差异有统计学意义(χ2=13.579,P=0.007)。结论乌蔹莓膏联合VAC应用于高位复杂性肛瘘手术患者,能够显著提高术后创面愈合速度、缓解创面疼痛、减少创面细菌生长并降低复发率。
[Abstract]:Objective to investigate the effect of Ampelopsis japonica ointment combined with negative pressure assisted healing system (VAC) on wound healing after high complex anal fistula. Methods from January to October 2016, 72 patients with high complex anal fistula were randomly divided into control group and observation group with 36 cases in each group. The control group was treated with routine wound disinfection and vaseline gauze after operation, and then fixed with dressing. In the observation group, the wounds were routinely disinfected with Ampelopsis japonica ointment first, the wounds were covered with isolation pad, and then treated with VAC. The wound healing speed, pain degree, bacterial detection rate and recurrence rate within half a year were compared between the two groups. Results the wound healing rate on the 10th day after operation [(45.7 卤2.1) vs (22.1 卤1.6)%], on the 15th day after operation [(76.2 卤1.7) vs. (39.7 卤1.5)%], on the 10th day after operation (8.3vs.44.4%), at 6 months after operation (2.7vs.16.7%) was higher than that in the control group. The difference was statistically significant (P0.05), and the pain assessment in the observation group was lighter than that in the control group on the 7th day after operation (蠂 ~ 2 ~ 2 ~ (13.579) P ~ (0.007). Conclusion the application of Ampelopsis japonica ointment combined with VAC in patients with high complex anal fistula can significantly improve the wound healing rate, relieve the wound pain, reduce the bacterial growth and reduce the recurrence rate.
【作者单位】：南京中医药大学第三附属医院全国肛肠病医疗中心;
【基金】：南京市科技发展计划基金资助项目(201503033)
【分类号】：R657.16

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