清蛋白与前清蛋白和C-反应蛋白检测对普外科患者术后感染的诊断研究
发布时间：2018-08-13 10:27
【摘要】：目的探讨清蛋白、前清蛋白和C-反应蛋白检测在普外科患者术后手术部位感染的诊断价值。方法选择医院2014年2月-2016年2月普外科手术患者320例,所有患者术前均确诊无感染,分别于术后12、24h、3d和7d取血标本检测清蛋白、前清蛋白和C-反应蛋白(CRP),监测所有患者于术后7d内是否发生感染;根据诊断结果将患者分为感染组27例和未感染组293例,比较两组术前、术后不同时间点的清蛋白、前清蛋白和CRP水平。结果术后发生感染患者27例,感染率8.44%,共检出病原菌36株,其中革兰阴性菌10株占27.78%,革兰阳性菌16株占44.44%,真菌10株占27.78%;两组患者清蛋白、前清蛋白、CRP在术前2h比较差异均无统计学意义,两组术后12、24h、3d、7d感染组患者清蛋白、前清蛋白、CRP明显低于术前,且感染组患者明显低于未感染组(P0.05),两组患者术后12、24h、3d、7dCRP均明显高于术前2h,且感染组明显高于对照组(P0.05);清蛋白、前清蛋白、CRP、清蛋白+前清蛋白、清蛋白+CRP、前清蛋白+CRP、清蛋白+前清蛋白+CRP 7种诊断方案对患者术后感染的诊断敏感度、特异度比较,以清蛋白+前清蛋白+CRP方案的诊断敏感度、特异度最佳。结论采用清蛋白+前清蛋白+CRP实验数据诊断普外科患者术后手术部位感染,时效性和客观性均较好,具有一定的临床价值。
[Abstract]:Objective to investigate the diagnostic value of detection of albumin, prealbumin and C-reactive protein in postoperative surgical site infection of patients in general surgery. Methods 320 patients undergoing general surgery from February 2014 to February 2016 were selected. All the patients were diagnosed as having no infection before operation. Prealbumin and C-reactive protein (CRP), were used to monitor whether infection occurred in all the patients within 7 days after operation. According to the diagnosis, the patients were divided into infected group (n = 27) and uninfected group (n = 293). The serum albumin at different time points before operation and at different time points after operation were compared between the two groups. Prealbumin and CRP levels. Results there were 27 cases of postoperative infection, the infection rate was 8.44%. A total of 36 strains of pathogenic bacteria were detected, of which 10 strains were Gram-negative bacteria (27.78%), 16 strains were Gram-positive bacteria (44.44%), and 10 strains were fungi (27.78%). There was no significant difference in serum protein and protein levels between the two groups at 2 hours before operation. The levels of serum protein and protein of prealbumin were significantly lower in the two groups than those in the pre-operation group at 12: 24 hours after operation for 3 days and 7 days after operation, and no significant difference was found between the two groups. The CRP of the infection group was significantly higher than that of the control group (P0.05), and the CRP of the infection group was significantly higher than that of the control group (P0.05), and the CRP of the infection group was significantly higher than that of the control group (P0.05), and the CRP of the two groups was significantly higher than that of the control group (P0.05). The sensitivity and specificity of seven diagnostic protocols of albumin prealbumin (CRP) and prealbumin (CRP) for postoperative infection were compared. The diagnostic sensitivity and specificity of CRP regimen were the best. Conclusion using the CRP data of albumin prealbumin to diagnose postoperative infection of surgical site in patients with general surgery is of good timeliness and objectivity and has certain clinical value.
【作者单位】： 河南省南阳市中医院外一科;
【分类号】：R619.3
本文编号：2180698
[Abstract]:Objective to investigate the diagnostic value of detection of albumin, prealbumin and C-reactive protein in postoperative surgical site infection of patients in general surgery. Methods 320 patients undergoing general surgery from February 2014 to February 2016 were selected. All the patients were diagnosed as having no infection before operation. Prealbumin and C-reactive protein (CRP), were used to monitor whether infection occurred in all the patients within 7 days after operation. According to the diagnosis, the patients were divided into infected group (n = 27) and uninfected group (n = 293). The serum albumin at different time points before operation and at different time points after operation were compared between the two groups. Prealbumin and CRP levels. Results there were 27 cases of postoperative infection, the infection rate was 8.44%. A total of 36 strains of pathogenic bacteria were detected, of which 10 strains were Gram-negative bacteria (27.78%), 16 strains were Gram-positive bacteria (44.44%), and 10 strains were fungi (27.78%). There was no significant difference in serum protein and protein levels between the two groups at 2 hours before operation. The levels of serum protein and protein of prealbumin were significantly lower in the two groups than those in the pre-operation group at 12: 24 hours after operation for 3 days and 7 days after operation, and no significant difference was found between the two groups. The CRP of the infection group was significantly higher than that of the control group (P0.05), and the CRP of the infection group was significantly higher than that of the control group (P0.05), and the CRP of the infection group was significantly higher than that of the control group (P0.05), and the CRP of the two groups was significantly higher than that of the control group (P0.05). The sensitivity and specificity of seven diagnostic protocols of albumin prealbumin (CRP) and prealbumin (CRP) for postoperative infection were compared. The diagnostic sensitivity and specificity of CRP regimen were the best. Conclusion using the CRP data of albumin prealbumin to diagnose postoperative infection of surgical site in patients with general surgery is of good timeliness and objectivity and has certain clinical value.
【作者单位】： 河南省南阳市中医院外一科;
【分类号】：R619.3
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1 曲林林;丁连安;;清蛋白、前清蛋白和血清超敏C反应蛋白检测对普外科病人术后感染的诊断意义[J];青岛大学医学院学报;2007年02期
，本文编号：2180698
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