术中应用抗菌药物冲洗对永久起搏器植入患者炎症指标与术后囊袋感染干预效果观察
发布时间：2018-08-17 19:46
【摘要】：目的观察永久起搏器植入手术过程中预防性进行抗菌药物冲洗对患者术后囊袋的感染情况,探讨起搏器植入术中行抗菌药物冲洗的价值。方法选择2013年2月-2015年2月医院在起搏器植入手术中接受抗菌药物冲洗的78例患者为观察组,将资料相仿的78例未接受抗菌药物冲洗的植入患者为对照组,观察手术前后患者血清炎性标志物的变化,并对术后囊袋感染情况进行跟踪随访。结果术前两组血清白细胞计数(WBC)、C-反应蛋白(CRP)、白细胞介素-1(IL-1)、白细胞介素6(IL-6)、降钙素原(PCT)相仿;手术后两组血清WBC、CRP、IL-6、PCT显著高于术前(P0.05),观察组术后72h和术后1周血清WBC[(11.25±2.15)109/L、(8.03±1.68)109/L]、CRP[(39.25±6.25)mg/L、(14.36±3.36)mg/L]、IL-1[(20.63±2.93)ng/ml、(17.47±2.84)ng/ml]、IL-6[(21.72±2.94)ng/ml、(18.52±1.86)ng/ml]及PCT[(1.34±0.56)μ.56、(0.85±0.32)μ.32]显著低于对照组(P0.05);观察组术后囊袋感染率(术后1、3、6、12个月分别为0、2.56%、3.85%、8.97%)明显低于对照组(P0.05)。结论永久起搏器植入手术过程中进行抗菌药物囊袋冲洗有利于预防术后囊袋感染,降低患者手术感染风险,对于患者预后具积极防治价值。
[Abstract]:Objective to investigate the effect of prophylactic washing with antibiotics during permanent pacemaker implantation on postoperative bag infection in patients, and to explore the value of anti-bacterial irrigation in pacemaker implantation. Methods from February 2013 to February 2015, 78 patients who received antibiotics washing during pacemaker implantation were selected as observation group and 78 patients who were not irrigated with antimicrobial agents as control group. To observe the changes of serum inflammatory markers before and after operation and follow up the postoperative cystic bag infection. Results the serum leukocyte count of the two groups before operation was similar to that of (WBC) C- reactive protein (CRP), interleukin-1 (IL-1), interleukin 6 (IL-6) and procalcitonin (PCT). 鎵嬫湳鍚庝袱缁勮娓匴BC,CRP,IL-6,PCT鏄捐憲楂樹簬鏈墠(P0.05),瑙傚療缁勬湳鍚，
本文编号：2188709
[Abstract]:Objective to investigate the effect of prophylactic washing with antibiotics during permanent pacemaker implantation on postoperative bag infection in patients, and to explore the value of anti-bacterial irrigation in pacemaker implantation. Methods from February 2013 to February 2015, 78 patients who received antibiotics washing during pacemaker implantation were selected as observation group and 78 patients who were not irrigated with antimicrobial agents as control group. To observe the changes of serum inflammatory markers before and after operation and follow up the postoperative cystic bag infection. Results the serum leukocyte count of the two groups before operation was similar to that of (WBC) C- reactive protein (CRP), interleukin-1 (IL-1), interleukin 6 (IL-6) and procalcitonin (PCT). 鎵嬫湳鍚庝袱缁勮娓匴BC,CRP,IL-6,PCT鏄捐憲楂樹簬鏈墠(P0.05),瑙傚療缁勬湳鍚，
本文编号：2188709
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