骨疏康颗粒联合PKP治疗骨质疏松性椎体压缩性骨折的临床疗效观察

发布时间：2018-08-26 11:23

【摘要】：目的观察骨疏康颗粒联合PKP手术对骨质疏松性椎体压缩骨折患者的近中期治疗效果。方法把明确诊断为骨质疏松性椎体压缩骨折的患者随机分成试验组和对照组,两组患者分别接受不同的治疗方法,其中试验组患者接受的治疗为PKP+骨疏康颗粒+常规抗骨质疏松,对照组患者接受的治疗为PKP+常规抗骨质疏松。分别对两组患者术前、术后1周、3月和6月的VAS评分、骨密度、Oswestry功能障碍指标(ODI)以及影像学指标进行记录,通过对这些指标进行分析来比较两组的近中期治疗效果。结果在术后各个观察点,两组患者的VAS评分、ODI评分均明显低于术前,随着时间的推移,试验组的降低幅度更为显著(P0.05);在术后各个观察点,两组患者的影像学指标均明显优于术前(P0.05),术后同时期两组间进行影像学比较,没有显著差异(P0.05);术后6月时,试验组和对照组的总有效率分别为85.72%、66.67%,前者明显高于后者(P0.05)。结论 PKP手术能够迅速改善OVCF患者的椎体高度,术后联合骨疏康颗粒进行治疗,能够快速缓解疼痛、改善骨密度水平,近中期疗效更为满意。
[Abstract]:Objective to observe the effect of Gushukang granule combined with PKP operation on the treatment of osteoporotic vertebral compression fracture in the near and medium term. Methods the patients diagnosed as osteoporotic vertebral compression fractures were randomly divided into two groups: the experimental group and the control group. The experimental group was treated with PKP Gushukang granule and the control group was treated with PKP routine anti-osteoporosis. The VAS scores, bone mineral density (BMD) Oswestry dysfunction index (ODI) and imaging indexes were recorded before operation, 1 week, 3 months and 6 months after operation in the two groups, and the results of treatment in the near and medium term were compared by analyzing these indexes. Results the scores of VAS and ODI in both groups were significantly lower than those before operation at each observation point after operation, and the decrease was more significant in the experimental group with the passage of time (P0.05). The imaging indexes of the two groups were significantly better than those of the pre-operation (P0.05), but there was no significant difference between the two groups in the same period after operation (P0.05); at 6 months after operation, the total effective rate of the experimental group and the control group was 85.72 and 66.67, the former significantly higher than the latter (P0.05). Conclusion PKP operation can rapidly improve the vertebral height of OVCF patients. The treatment combined with Gushukang granule can relieve pain quickly and improve bone mineral density. The curative effect is more satisfactory in the near and medium term.
【作者单位】：福建中医药大学附属人民医院
【分类号】：R687.3

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