基于文献计量学和社会网络分析法分析国内椎间盘退变领域的研究热点和发展趋势

发布时间：2018-10-08 21:51

【摘要】：目的:采用文献计量的方法 ,从社会网络分析的角度挖掘国内椎间盘退变相关研究领域的核心作者和学术团队,分析其研究成果和发展趋势。方法:将检索词"退变"、"退行性改变"与检索词"腰椎"、"椎间盘"、"颈椎"、"胸椎"、"腰"等自由组合,检索三大中文电子数据库中公开发表的期刊文献,包括相关期刊论文(CNKI)、万方数据知识服务平台(Wanfang Data)和中国生物医学文献数据库(CBM),出版时间不作限定,检索日期为2015年5月4日。数据信息的提取采用Regex Buddy软件,核心作者和学术团队的评定采用普莱斯定律和综合指数相结合的方法,数据挖掘的结果以Netdraw软件进行可视化表达。分析各团队的学术思想、行业现状及发展趋势。结果:研究共纳入3361篇中文文献,挖掘核心作者54人、学术团队10个。分析结果表明,该领域的研究主要集中于以下几大热门方向:发病机制及药物作用机理研究(1964篇,占总量的58.43%);手术相关研究(1035篇,占总量的30.79%);细胞及分子生物学研究(979篇,占总量的29.13%);生物力学相关研究(854篇,占总量的25.41%);动物学研究(686篇,占总量的20.41%);影像学相关研究(348篇,占总量的10.35%)。结论 :机制研究是目前椎间盘退变领域的研究热点,学者们已从整体动物水平、细胞水平和分子水平等多层次对退变的发生和发展机理进行了探讨,如何将基础研究的成果转化为临床干预手段,切实有效地延缓甚至逆转椎间盘的退行性改变,可能成为今后研究的发展方向。
[Abstract]:Objective: to analyze the research results and development trends of the core authors and academic teams in the field of intervertebral disc degeneration in China from the point of view of social network analysis with the method of literature measurement. Methods: the key words "degeneration", "degenerative change" and "lumbar vertebrae", "intervertebral disc", "cervical vertebra", "thoracic vertebra" and "waist" were combined to search the published journals published in three Chinese electronic databases. There is no limit to the publishing time of the Chinese periodical full-text database (CNKI), Wanfang data knowledge service platform (Wanfang Data) and the Chinese biomedical literature database (CBM),. The retrieval date is May 4 2015. Regex Buddy software is used to extract data information. The evaluation of core authors and academic teams adopts the method of combining Price's law and comprehensive index. The results of data mining are visualized by Netdraw software. Analyze the academic thoughts, current situation and development trend of each team. Results: a total of 3361 Chinese articles were included in the study, 54 core authors and 10 academic teams were excavated. The results show that the research in this field is mainly focused on the following hot areas: pathogenesis and drug action mechanism (1964 articles, 58.43% of the total), surgical related studies (1035 articles, 30.79% of the total), cell and molecular biology studies (979 papers, 58.43% of the total), Biomechanical studies (854, 25.41%), zoology (686, 20.41%) and image-related studies (348, 10.35%) accounted for 29.13% of the total. Conclusion: the study of mechanism is a hot topic in the field of intervertebral disc degeneration at present. The mechanism of degeneration has been discussed from the animal level, cell level and molecular level. How to transform the achievements of basic research into clinical intervention and delay or even reverse the degenerative change of intervertebral disc effectively may become the development direction of future research.
【作者单位】：中国中医科学院望京医院脊柱二科;
【基金】：北京市自然科学基金青年项目(No.7164313) 中国中医科学院科技创新优势团队项目(No.YS1304);中国中医科学院名医名家项目(CM2014GD1010)
【分类号】：R681.53;G353.1

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