老年髋部骨折手术前后血清B型尿钠肽和心肌肌钙蛋白的变化

发布时间：2018-10-12 15:15

【摘要】：[目的]探讨血清B型尿钠肽(BNP)、心肌肌钙蛋白T(c Tn T)检测在老年髋部骨折围手术期心脏评估的意义。[方法]2010年1月~2015年1月于本院进行治疗的142例髋部骨折患者分为低龄组和高龄组,将两组患者术前24 h及术后1、3 d血清BNP、c Tn T水平进行检测及比较。[结果]两组BNP检测结果显示:低年龄组及高年龄组术后1、3 d均较术前1 d升高,差异有统计学意义(P0.05),高年龄组在相同时间点明显高于低年龄组,尤其是术后变化更加明显,相同时间点两组间比较差异有统计学意义(P0.05)。两组c Tn T测量结果显示:低年龄组及高年龄组术后1、3 d均较术前1 d升高,差异有统计学意义(P0.05),术后高年龄组在相同时间点明显高于低年龄组,术后3 d两组间比较差异有统计学意义(P0.05),术前1 d、术后1 d高年龄组有升高趋势,但相同时间点两组间比较差异无统计学意义(P0.05)。患者年龄与血清BNP、c Tn T检测值的Pearson相关分析显示具有一定相关性。[结论]血清BNP、c Tn T是敏感的心肌梗死及心力衰竭标志物,二者在老年髋部骨折围手术期心脏评估中动态变化价值较高,骨折患者随其年龄及手术升高变化,具有一定规律性。
[Abstract]:[objective] to investigate the clinical significance of cardiac troponin T (c Tn T) detection in elderly patients with hip fracture by serum type B urinary natriuretic peptide (BNP),). [methods] 142 patients with hip fracture treated in our hospital from January 2010 to January 2015 were divided into two groups: the low age group and the old age group. The serum BNP,c Tn T levels were measured and compared between the two groups 24 hours before operation and 1: 3 days after operation. [results] the results of BNP detection in the two groups showed that the level of BNP in the low age group and the high age group was significantly higher than that in the preoperation 1 day after operation (P0.05). The changes in the high age group were significantly higher than those in the low age group at the same time point, especially after the operation. There was significant difference between the two groups at the same time (P0.05). The results of c Tn T measurement in the two groups showed that 1 day after operation, 3 days after operation in the low age group and the high age group were significantly higher than that in the low age group (P 0.05), and the difference was statistically significant (P0.05). At the same time after operation, the high age group was significantly higher than the low age group. There was a significant difference between the two groups 3 days after operation (P0.05), 1 day before surgery, 1 day after the operation of the high age group has an upward trend, but at the same time point between the two groups there was no significant difference (P0.05). The Pearson correlation analysis of age and serum BNP,c Tn T showed a certain correlation. [conclusion] Serum BNP,c Tn T is a sensitive marker of myocardial infarction and heart failure. The dynamic changes of serum BNP,c Tn T in elderly patients with hip fracture in perioperative period are higher.
【作者单位】：山东省济南市中心医院骨外科;山东省济南市中心医院心内科;
【分类号】：R687.3

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