骨科创伤患者感染病原菌分布及耐药性分析

发布时间：2018-10-12 19:09

【摘要】：目的回顾性观察骨科创伤患者感染病原菌分布情况及耐药性特点,为临床合理选取抗菌药物提供参考依据。方法选取2013年6月-2016年5月医院骨科创伤患者1196例,分析其感染患者病原菌分布及耐药率。结果 1 196例骨科创伤,感染率为2.01%;24例感染患者共分离病原菌36株,其中革兰阴性菌25株占69.44%,高于革兰阳性菌的27.78%、真菌的2.78%,差异有统计学意义(P0.05);铜绿假单胞菌对头孢唑林、头孢西丁耐药率均达100.00%,大肠埃希菌及肺炎克雷伯菌对氨苄西林、头孢唑林、头孢西丁耐药率达100.00%,鲍氏不动杆菌对头孢唑林、头孢西丁、呋喃妥因耐药率为100.00%,阴沟肠杆菌对头孢唑林和头孢西丁耐药率达100.00%,金黄色葡萄球菌、表皮葡萄球菌对青霉素G、苯唑西林耐药率均为100.00%。结论骨科创伤患者感染后尽快采集标本实施病原菌培养及鉴定,严格遵循药敏试验结果及时调整抗菌药物,避免耐药菌产生。
[Abstract]:Objective to observe the distribution of pathogenic bacteria and drug resistance in orthopedic trauma patients and to provide reference for the rational selection of antimicrobial agents in clinic. Methods 1196 patients with orthopedic trauma from June 2013 to May 2016 were selected and the distribution of pathogenic bacteria and drug resistance rate were analyzed. Results among 1 196 orthopedic trauma patients, the infection rate was 2.01%. A total of 36 pathogenic bacteria were isolated from 24 patients, of which 25 Gram-negative bacteria accounted for 69.444.This was higher than that of Gram-positive bacteria 27.78 and fungi 2.78, the difference was statistically significant (P0.05), Pseudomonas aeruginosa for cefazolin, The resistance rates of Escherichia coli and Klebsiella pneumoniae to ampicillin, cefazolin and cefoxitin were 100.00. Acinetobacter baumannii was resistant to cefazolin and cefoxitin. The resistance rate of Enterobacter cloacae to cefazolin and cefoxitin was 100.00.Staphylococcus aureus, Staphylococcus epidermidis and Staphylococcus epidermidis were all resistant to penicillin G and oxacillin. Conclusion the samples of orthopedic trauma patients were collected as soon as possible to culture and identify the pathogenic bacteria, and the results of drug sensitivity test were strictly followed to adjust the antimicrobial agents in time to avoid the emergence of drug-resistant bacteria.
【作者单位】：遵义市第一人民医院骨科;
【分类号】：R446.5;R68

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