血栓弹力图指导心脏手术输血对术后出血量的影响meta分析

发布时间：2018-10-18 06:53

【摘要】：目的评价血栓弹力图(thromboelastography,TEG)与常规检测指导心脏手术输血对术后出血量的影响,为治疗决策提供依据。方法以"Thromboelastography、TEG、血栓弹力图、血栓弹力描记图"为检索词检索Pub Med、Embase、The Cochrane Library、中国生物医学文献数据库和中国期刊网全文数据库建库至2015年2月关于TEG与常规检测指导心脏手术输血对术后出血量影响的随机对照试验或回顾性队列研究,对符合纳入标准的文献提取资料、评估方法学质量,并采用Rev Man5.3软件进行meta分析。结果最终纳入7篇文献共计689例患者,其中5篇为高质量研究,2篇为低质量研究。meta分析结果显示:TEG与常规检测指导心脏手术输血对术后出血量的影响差异有统计学意义[WMD=-45.67,95%CI(-80.32,-11.03),P0.05]。结论与常规检测指导心脏手术输血比较,TEG指导能明显减少患者术后出血量。
[Abstract]:Objective to evaluate the effect of thromboelastography (thromboelastography,TEG) and routine test on postoperative blood loss in cardiac surgery. Methods "Thromboelastography,TEG, thromboelastogram" was used. "Thromboelastography" search Pub Med,Embase,The Cochrane Library, Chinese Biomedical Literature Database and China Journal Web Full-text Database until February 2015 on TEG and routine testing to guide Blood Transfusion in Cardiac surgery for postoperative Hemorrhage Volume Random controlled trials or retrospective cohort studies, The quality of methodology was evaluated and meta analysis was carried out with Rev Man5.3 software. Results A total of 689 patients were included in 7 articles, of which 5 were of high quality and 2 were of low quality. The results of meta analysis showed that there was a significant difference between TEG and routine blood transfusion guidance in cardiac surgery on postoperative bleeding volume [WMD=-45.67,95%CI (-80.32 卤11.03), P0.05]. Conclusion TEG guidance can significantly reduce postoperative blood loss in patients with cardiac surgery as compared with conventional blood transfusion guidance.
【作者单位】：第四军医大学西京医院急诊科;第四军医大学西京医院心内科;第四军医大学西京医院骨科;
【基金】：军队重大课题子项目(AWS14C003-01) 西京医院学科助推计划(XJZT14D10)
【分类号】：R654.2

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