新型国产涤纶补片在先天性心脏病外科治疗中的临床应用

发布时间：2018-11-01 14:29

【摘要】：目的采用新型国产涤纶补片进行临床对照试验,以评估其在先天性心脏病的外科治疗中的疗效和安全性。方法选取2014年1月-2015年6月于兰州大学第一医院心外科住院的并符合纳入标准的40例先天性心脏病患者,试验模式为随机对照试验,将符合入选标准的40名患者平均随机分为两组,其中试验组20例患者采用新型国产涤纶补片进行先天性心脏病的手术治疗,对照组的20例患者则采用已上市的某进口心脏补片。通过收集两组患者术前及术后的胸片、心脏彩超、心电图及实验室检查,观察两组患者术后有无残余分流、心功能、肝功能、肾功能、凝血功能及其他相关指标,评价新型涤纶补片的治疗效果及安全性。结果试验组患者的治疗效果、有效率、补片使用体验、安全性等指标与对照组相比无明显差异,可考虑在临床逐渐推广使用。
[Abstract]:Objective to evaluate the efficacy and safety of new domestic polyester patch in the surgical treatment of congenital heart disease. Methods from January 2014 to June 2015, 40 patients with congenital heart disease who were hospitalized in Department of Cardiology, first Hospital of Lanzhou University and who met the inclusion criteria, were selected. The trial model was a randomized controlled trial. 40 patients who met the criteria were randomly divided into two groups: the experimental group (n = 20) was treated with a new type of domestic polyester patch for congenital heart disease, and the control group (n = 20) was treated with an imported heart patch. By collecting chest radiographs, echocardiography, electrocardiogram and laboratory examination before and after operation, we observed whether there were residual shunt, cardiac function, liver function, renal function, coagulation function and other related indexes in the two groups. To evaluate the efficacy and safety of new polyester patch. Results there was no significant difference in treatment effect, effective rate, patch use experience and safety between the trial group and the control group.
【学位授予单位】：兰州大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R654.2

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