免气腹腹腔镜胆道探查术对患者凝血功能的影响

发布时间：2018-11-01 16:43

【摘要】：目的探讨免气腹腹腔镜胆道探查术对患者凝血功能的影响。方法选择择期行免气腹腹腔镜胆道探查术的26例患者,分别测定腹壁悬吊前、悬吊中、悬吊后及术后4组血浆样本中组织因子活性(tissue factor activity,TF:A)、凝血酶-抗凝血酶Ⅲ复合物(thrombin-antithrombinⅢcomplexes,TAT)、血浆组织型纤溶酶原激活物(tissue-type plasminogen activator,t-PA)和纤溶酶原激活物抑制物(plasminogen activator inhibitor-1,PAI-1)的变化。结果 (1)TF:A值在4组中差异有统计学意义(P0.01),两两比较显示,悬吊后与悬吊前、悬吊中、术后相比差异均有统计学意义(P0.01)。(2)TAT值在4组中差异无统计学意义(P0.05)。(3)t-PA值在4组中差异有统计学意义(P0.01),两两比较显示,悬吊后与悬吊前、悬吊中相比差异有统计学意义(P0.01)。术后与悬吊前、悬吊中相比差异有统计学意义(P0.01)。(4)PAI值在4组中差异有统计学意义(P0.01),两两比较显示,悬吊后与悬吊前、悬吊中、术后相比差异均有统计学意义(P0.01)。结论免气腹腹腔镜胆道探查术对患者凝血功能的影响处于机体自身可调节范围内,术后早期无高凝状态出现。
[Abstract]:Objective to investigate the effect of free pneumoperitoneum laparoscopic exploration of bile duct on coagulation function of patients. Methods Twenty six patients undergoing pneumoperitoneum laparoscopic choledochectomy were selected to measure the tissue factor activity (tissue factor activity,TF:A) in plasma samples before, during and after abdominal wall suspension, respectively. The changes of thrombin-antithrombin 鈪，

本文编号：2304502