不同年龄段乳腺癌保乳手术患者临床病理特征及预后分析
发布时间:2018-11-05 11:00
【摘要】:目的:研究不同年龄段乳腺癌保乳治疗患者的临床病理特征,探究年龄是否是影响患者预后的独立危险因素。方法:回顾性分析我院2008年6月-2011年12月接受保乳手术治疗的456例乳腺癌患者的临床资料,根据诊断乳腺癌时年龄不同分年轻组(年龄≤35岁)和中老年组(年龄35岁),比较2组患者临床病理特征及统计两组患者无局部复发生存率、无远处转移生存率以及总体生存率。结果:456例患者中,年轻组80例,中老年组376例。与中老年组相比,年轻组患者中淋巴结转移数≥4的患者比例较大,且激素受体阴性率较高。年轻组5年无局部复发生存率、5年无远处转移生存率以及5年总体生存率分别为82.3%、83.4%、88.1%;中老年组的上述指标分别为87.3%、88.3%、88.2%。多因素COX分析显示:年龄较小(≤35岁)、组织学分级高以及术后未行化疗放疗是影响局部复发、远处转移及总生存率的危险因素。结论:年轻乳腺癌患者的病理特征及预后较为特殊,虽然年轻组保乳术后局部复发及远处转移风险较高,但其死亡率并未增加,仍建议保乳治疗。
[Abstract]:Objective: to study the clinicopathological characteristics of breast cancer patients in different age groups and to explore whether age is an independent risk factor for the prognosis of breast cancer patients. Methods: the clinical data of 456 breast cancer patients who received breast conserving surgery from June 2008 to December 2011 were analyzed retrospectively. According to the age of breast cancer diagnosis, the patients were divided into young group (鈮,
本文编号:2311856
[Abstract]:Objective: to study the clinicopathological characteristics of breast cancer patients in different age groups and to explore whether age is an independent risk factor for the prognosis of breast cancer patients. Methods: the clinical data of 456 breast cancer patients who received breast conserving surgery from June 2008 to December 2011 were analyzed retrospectively. According to the age of breast cancer diagnosis, the patients were divided into young group (鈮,
本文编号:2311856
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