骨代谢生化指标与绝经后骨质疏松性腰椎骨折相关性分析
发布时间：2018-12-08 09:59
【摘要】：目的探讨骨代谢生化指标与绝经后骨质疏松性腰椎骨折相关性,进而预测绝经后骨质疏松性合并腰椎骨折风险。方法回顾性分析100例绝经后骨质疏松症患者的临床资料,包括绝经后骨质疏松症腰椎无骨折患者50例和绝经后骨质疏松症合并腰椎骨折患者50例,记录并观察髋部、腰椎骨密度、骨代谢生化标志物Ⅰ型前胶原氨基端前肽(P1NP)、Ⅰ型胶原羧基端肽β特殊序列(β-CTX)、骨钙素N端中分子(N-MID)、25-羟基维生素D[25-(OH)VitD]和血清Ca2+。结果P1NP、β-CTX和25-(OH)VitD的差异具有统计学意义(P0.05),绝经后骨质疏松性腰椎骨折与血清P1NP呈正相关(P0.05),25-(OH)VitD呈负相关(P0.05),β-CTX无相关性(P0.05)。结论骨代谢标志物P1NP、25-(OH)VitD能够很好地预测绝经后骨质疏松腰椎骨折风险,骨密度预测骨质疏松症骨折风险具有一定局限性。
[Abstract]:Objective to investigate the correlation between bone metabolism and postmenopausal osteoporotic lumbar vertebrae fracture, and to predict the risk of postmenopausal osteoporosis complicated with lumbar vertebra fracture. Methods the clinical data of 100 patients with postmenopausal osteoporosis were retrospectively analyzed, including 50 cases of postmenopausal osteoporosis without lumbar fracture and 50 cases of postmenopausal osteoporosis with lumbar vertebral fracture. Hip was recorded and observed. Lumbar vertebrae bone mineral density, bone metabolism biochemical marker type I procollagen amino terminal prepeptide (P1NP), type 鈪，
本文编号：2368158
[Abstract]:Objective to investigate the correlation between bone metabolism and postmenopausal osteoporotic lumbar vertebrae fracture, and to predict the risk of postmenopausal osteoporosis complicated with lumbar vertebra fracture. Methods the clinical data of 100 patients with postmenopausal osteoporosis were retrospectively analyzed, including 50 cases of postmenopausal osteoporosis without lumbar fracture and 50 cases of postmenopausal osteoporosis with lumbar vertebral fracture. Hip was recorded and observed. Lumbar vertebrae bone mineral density, bone metabolism biochemical marker type I procollagen amino terminal prepeptide (P1NP), type 鈪，
本文编号：2368158
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