融合术后压缩载荷下腰椎粘弹性的研究

发布时间：2018-12-16 14:28

【摘要】：通过对比前路融合术前后双节段腰椎的蠕变特性,研究日常静态载荷下融合术对腰椎的粘弹性的影响.选择10组L3-L5双节段熟龄山羊腰椎制作样本,融合组样本采用钢板前路融合术.在L3上表面施加0.4 Mpa的压缩载荷30 min,模拟人体坐姿或直立状态腰椎受力情况.观察融合术前后样本的蠕变曲线,通过蠕变曲线拟合计算出粘弹性参数.与完好组脊柱相比,融合术后脊柱整体蠕变变形显著减小;融合术后样本总体弹性特性参数显著增大,其中包括快速响应刚度S1和慢速响应刚度S2;融合术后样本总体粘性特性参数τ2显著减小,其中慢速响应粘性参数显著减小,快速响应粘性参数τ1无显著性差异;融合术后样本的位移显著减小,其中包括术后慢速响应位移L·S-12,弹性响应位移L·SE-1,快速响应位移L·S-11;平衡位移和平衡时间显著减小.快速和慢速响应分别对应骨组织和间盘组织.融合术后样本下椎间盘作用被钢板替换导致整体粘性下降,刚度上升,融合术后样本的蠕变变形由于刚度的增大而显著降低.平衡时间和平衡位移降低说明融合后整体的缓冲能力下降,但是邻近节段承受的缓冲负载却增大.
[Abstract]:By comparing the creep characteristics of two segments of lumbar vertebrae before and after anterior fusion, the effects of fusion on the viscoelasticity of lumbar spine under daily static loading were studied. The lumbar vertebrae of 10 groups of L3-L5 adult goats were made, and the fusion group were treated with anterior fusion with steel plate. The compression load of 0.4 Mpa was applied on the upper surface of L3 for 30 min, to simulate the lumbar vertebrae force in the sitting position or upright state of human body. The creep curves of the samples before and after fusion were observed and the viscoelastic parameters were calculated by fitting the creep curves. Compared with the intact spinal column, the global creep deformation of the fusion group decreased significantly, and the overall elastic properties of the fusion group increased significantly, including the rapid response stiffness S1 and the slow response stiffness S2. After fusion, the viscosity parameter 蟿 2 of the whole sample decreased significantly, in which the viscosity parameter of slow response significantly decreased, and the viscosity parameter 蟿 1 of rapid response showed no significant difference. The displacement of the fusion samples decreased significantly, including slow response displacement L S-12, elastic response displacement L SE-1, fast response displacement L S-11, and equilibrium displacement and equilibrium time decreased significantly. The rapid and slow responses correspond to bone tissue and disc tissue, respectively. After fusion, the intervertebral disc was replaced by steel plate, which resulted in the decrease of the whole viscosity and the increase of the stiffness. The creep deformation of the specimen decreased significantly because of the increase of the stiffness. The decrease of equilibrium time and equilibrium displacement indicates that the whole buffer capacity decreases after fusion, but the buffer load of adjacent segments increases.
【作者单位】：北京航空航天大学生物与医学工程学院;
【基金】：国家自然科学基金资助项目(11372029、81672201)
【分类号】：R687.3

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