胰十二指肠切除患者术后感染影响因素分析

发布时间：2018-12-18 16:14

【摘要】：目的探讨胰十二指肠切除术术后感染的影响因素。方法通过医院HIS系统,提取某医院2014-2016年胰十二指肠手术全部病例,比较手术后感染的发生对住院天数、住院费用的影响;利用logistic回归模型,对手术后感染的影响因素进行分析。结果男性发生手术后感染的风险是女性的2.56倍(95%CI:1.127~5.834);开腹手术是手术后感染的保护因素,其OR值0.283(95%CI:0.131~0.614);术中输血超过1 000ml显著增大感染风险(OR=23.537,95%CI:10.927~50.698);年龄、手术时间对手术后感染的发生也有一定影响;发生手术后感染患者,其中位住院日延长5.96d,住院费用增加10.47万元。结论胰十二指肠切除术后感染延长了患者住院天数,增加了疾病负担。男性、腹腔镜和机器人术式、术中输血量超过1 000ml是手术后感染的高危因素,需要严格把握适应证,减少风险。
[Abstract]:Objective to investigate the influencing factors of infection after pancreaticoduodenectomy. Methods all cases of pancreaticoduodenal operation from 2014-2016 in a hospital were extracted by HIS system, and the effect of infection after operation on hospitalization days and hospital expenses was compared. Logistic regression model was used to analyze the influencing factors of postoperative infection. Results the risk of postoperative infection in male was 2.56 times higher than that in female (95%CI:1.127~5.834), open operation was the protective factor of post-operative infection, and OR value was 0.283 (95%CI:0.131~0.614). Intraoperative transfusion of more than 1 000ml significantly increased the risk of infection (OR=23.537,95%CI:10.927~50.698), age and operation time also affected the incidence of infection after operation. The patients with infection after operation, the hospitalization time was prolonged by 5.96 days, and the hospitalization cost was increased by 104700 yuan. Conclusion infection after pancreaticoduodenectomy prolonged the hospital stay and increased the burden of disease. Male, laparoscopic and robotic operation, intraoperative blood transfusion more than 1 000ml are the high risk factors of infection after surgery, need to strictly grasp the indications to reduce the risk.
【作者单位】：解放军总医院麻醉手术中心;解放军总医院医院管理研究所;
【基金】：中央保健委员会专项基金资助项目(11BJZ08)
【分类号】：R656

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