仙灵骨葆胶囊联合PKP技术治疗老年骨质疏松脊柱压缩性骨折的疗效分析
发布时间：2018-12-27 14:10
【摘要】：目的研究仙灵骨葆胶囊联合经皮椎体后凸成形术(PKP)技术对老年骨质疏松脊柱压缩性骨折的疗效。方法采用临床观察的方法,观察研究武汉市第一医院骨伤科2013年6月至2014年10月之间老年骨质疏松患者因脊柱压缩性骨折行PKP手术及抗骨质疏松治疗病例,选取80例病例,根据患者采取治疗方法的不同,分为实验组(中药组)和对照组(西药组)。实验组40例病例,其中男15例,女25例,治疗方法为:行PKP手术之后定期服用口服中成药仙灵骨葆胶囊+钙剂治疗(实验组);对照组40例,其中男16例,女24例,治疗方法为行PKP手术后定期服用阿伦磷酸钠+钙剂治疗(对照组:已知疗效确切安全)。对两组病例进行追踪随访,观察并记录各组病例PKP手术术前、手术后、服药治疗一个月、服药治疗三个月、服药治疗半年的JOA评分、疼痛评分(采用视觉模拟评分法(VAS)评级进行评分)、骨密度等数据。比较分析各组实验数据。结果两组病例PKP手术术前、手术后、服药治疗一个月、服药治疗三个月、服药治疗半年的JOA评分、VAS评分、骨密度无显著的统计学意义(P0.05)。结论仙灵骨葆结合PKP技术对老年骨质疏松脊柱压缩性骨折确有疗效且安全可靠。
[Abstract]:Objective to study the efficacy of Xianling Gubao capsule combined with percutaneous kyphoplasty (PKP) in the treatment of senile osteoporotic spinal compression fracture. Methods Clinical observation was used to observe and study the PKP operation and anti-osteoporosis treatment in elderly patients with osteoporosis from June 2013 to October 2014 in Department of Orthopedics and Trauma of the first Hospital of Wuhan City. 80 cases were selected. According to the different treatment methods, the patients were divided into experimental group (Chinese medicine group) and control group (western medicine group). There were 40 cases in the experimental group, including 15 males and 25 females. The treatment methods were as follows: after PKP operation, the patients were treated with oral Chinese patent medicine Xianling Gubao capsule calcium regularly (experimental group); 40 cases of control group, including 16 males and 24 females, were treated with alenophosphate calcium on a regular basis after PKP operation (control group: known to be safe and effective). The patients in both groups were followed up to observe and record the JOA scores before and after PKP operation for one month, three months and half a year before and after PKP operation. Pain score (VAS) score by visual analogue score), bone mineral density and other data. The experimental data of each group were compared and analyzed. Results there was no significant difference in JOA score, VAS score and bone mineral density (BMD) between the two groups before and after PKP operation for one month and three months (P0.05). Conclusion Xianling Gubao combined with PKP technique is effective and safe in the treatment of senile osteoporotic spinal compression fracture.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R687.3
本文编号：2393188
[Abstract]:Objective to study the efficacy of Xianling Gubao capsule combined with percutaneous kyphoplasty (PKP) in the treatment of senile osteoporotic spinal compression fracture. Methods Clinical observation was used to observe and study the PKP operation and anti-osteoporosis treatment in elderly patients with osteoporosis from June 2013 to October 2014 in Department of Orthopedics and Trauma of the first Hospital of Wuhan City. 80 cases were selected. According to the different treatment methods, the patients were divided into experimental group (Chinese medicine group) and control group (western medicine group). There were 40 cases in the experimental group, including 15 males and 25 females. The treatment methods were as follows: after PKP operation, the patients were treated with oral Chinese patent medicine Xianling Gubao capsule calcium regularly (experimental group); 40 cases of control group, including 16 males and 24 females, were treated with alenophosphate calcium on a regular basis after PKP operation (control group: known to be safe and effective). The patients in both groups were followed up to observe and record the JOA scores before and after PKP operation for one month, three months and half a year before and after PKP operation. Pain score (VAS) score by visual analogue score), bone mineral density and other data. The experimental data of each group were compared and analyzed. Results there was no significant difference in JOA score, VAS score and bone mineral density (BMD) between the two groups before and after PKP operation for one month and three months (P0.05). Conclusion Xianling Gubao combined with PKP technique is effective and safe in the treatment of senile osteoporotic spinal compression fracture.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R687.3
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